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Outline. Introduction Main Principles Computational Model and Results Experimental Preliminary Results Conclusions and Future Work. What are optical tweezers? . Motivation Manipulation : Cell/particle manipulation withouth physical contact;

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Outline

Outline

  • Introduction

  • Main Principles

  • Computational Model and Results

  • Experimental Preliminary Results

  • Conclusions and Future Work

Young Scientist's 1st International Baku Forum


What are optical tweezers

What are optical tweezers?

  • Motivation

  • Manipulation: Cell/particle manipulation withouth physical contact;

  • Miniaturization: Diagnostic devices (in vivo cells, ...)

  • Main Goals

  • Development of fiber optical tweezers;

  • Study of the forces:

    • Numerical models;

    • Design and optimization of fiber structures;

  • Fabrication of devices;

  • Field of application: Manipulation of Red Blood Cells.

Liu, Z. et al Opt. Express, OSA, 2006, 14, 12510-12516

Young Scientist's 1st International Baku Forum


Main principles

Main Principles

  • Particle placed in the focusing region of a laser beam:

  • Force  transference of momentum on the particle surface (reflections/refractions).

  • Scatering Force

  • Gradient Force

Ashkin, A., Dziedzic, J. M., Bjorkholm, J.E. and Chu, S. (1986),Opt Lett., 11, 288-290;

Ashkin, A. (1970),Phys. Rev. Lett., 24, 156-159.

Young Scientist's 1st International Baku Forum


Computational model and results

Computational model and Results

Lorentz Force (dipoles):

R. S. RODRIGUES RIBEIROet al, “ComputationalModelsfor New FiberOpticTweezers”, PhotonicSensors

Young Scientist's 1st International Baku Forum


Results

Results

Young Scientist's 1st International Baku Forum


Preliminary results

Preliminary Results

Experimental Preliminary Results

  • Lens – polimer:

    • radius ~ 30-40 μm;

  • Laser Diode 980 nm, P = 100mW;

  • Polystyrene particles:

R. S. Rodrigues Ribeiro, et al., New theoretical and experimental methods for the design of fiber optic tweezers, EWOFS, Poland,2013

Young Scientist's 1st International Baku Forum


Conclusion and future work

Conclusion and Future Work

  • Development of a 2D numerical model to calculate optical forces acting on a particle/cell;

  • Fabrication of lenses in optical fibers;

  • Implementation of a 3D numerical model;

  • Study of distinct fiber geometries;

  • Manipulation of RBC.

Young Scientist's 1st International Baku Forum


Outline

Thanks!

Young Scientist's 1st International Baku Forum


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