INTRODUCTION TO VIROLOGY. Prepared by: Miss Norzawani Jaffar Bsc ( Hons ) Biomedical Sciences, UKM. Lecture 16. Learning Outcomes. At the end of learning season, the student must be able to; Understand virology in definition. Explain the general structure for virus
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INTRODUCTION TO VIROLOGY
Bsc (Hons) Biomedical Sciences, UKM
At the end of learning season, the student must be able to;
The science which study the virus and viral diseases.
A genitic material containing either DNA or RNA genome that is able to alternate between intra and extra cellular states.
Is a microscopic infectious agent that can reproduce only inside a host cell.
The virus is usually very, very small compared to the size of a living cell (20 – 300 nm).
Viral components are assembled and don’t replicate
By “ division “.
Viruses need to host cell to produce their components
Viruses have a naked capsid or an envelope morphology.
Structure of virus
1- Nucleic acid(genome) :
DNA or RNA not both.
2- Capsid(protein coat) :
Which protect the genitic material.
a)Helical. b) Icosahedral.
3- Envelope :
That surrounds them then they are outside the cell.
Viruses spread by coughing and sneezing
Viruses are transmitted by the faecal-oral route such as
(Norovirus), via contact with contaminated hands, food, or water.
HIV is one of several viruses that are transmitted through sexual contact.
DNA viruses remember HHAPPPy.
*all DNA viruses replicate in the nucleus except POX replicate in the cytoplasm.
*all DNA viruses are dsDNA except PARVOssDNA.
*all DNA viruses are icosahedral except POX is complex.
*3 DNA viruses are naked PAP(Parvo, Adeno and Papova).
*all RNA viruses are ssRNA except REO is ds RNA.
*all RNA viruses replicate in the cytoplasm except ORB
(Orthomyxo, Retro and Borna) replicate in the nucleus.
*3 RNA viruses are non enveloped PCR (Picorna, Calici
*5 RNA viruses have icosahedral PCR+FT ( Flavi and
Adeno Virus cause Conjuctivitis Red Eye
Drugs that use for viral infections are called antiviral drugs.
Interferon: which stop or slow virus replication.
Vaccines: for antibody formation, before exposure to disease.
Immunoglobulins: are related to immune system and help to kill the virus.