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OESOPHAGEAL ATRESIA

OESOPHAGEAL ATRESIA. Anne Aspin 2010. Types of oesophageal atresia and fistula. 86%. 7%. 4%. Types continued. 1%. <1. <1. History. First case recorded Durston (1670) Gibson (1697) first recorded with fistula Ladd (1939) first staged repair

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OESOPHAGEAL ATRESIA

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  1. OESOPHAGEAL ATRESIA Anne Aspin 2010

  2. Types of oesophageal atresia and fistula 86% 7% 4%

  3. Types continued 1% <1 <1

  4. History • First case recorded Durston (1670) • Gibson (1697) first recorded with fistula • Ladd (1939) first staged repair • Height (1941) first successful primary repair.

  5. Survival rate of around 90% • Incidence 1: 4500 • Antenatal diagnosis – polyhydramnios and absent stomach 56% predictive of OA.

  6. After birth • Large NG tube • CXR, AXR • Replogle tube, 10 min suction to pharynx

  7. Associated anomalies • 50% associated anomalies • Cardiac 29% • Vertebral, Anorectal, Cardiac, Tracheo, Oesophageal, Renal, Limb

  8. CHARGE, Coloboma, Heart defects, Atresia choanal, retarded growth and development, Genital Hypoplasia, Ear

  9. Table 1 • Cardiovascular 29% • Gastro intestinal (anorectal 14%) 27% • Genito urinary 13% • Vertebral and skeletal 10% • Respiratory 6% • Genetic 4%

  10. Table 2 • Risk classification for OA • Group BW Major cardiac survival defect 1 >1500 No 96% 2 <1500 or Yes 60% 3 <1500 and Yes 18%

  11. Primary repair • Paralyse and ventilate 5 days post op • Long gap – gastrostomy and assessment of gap, may leave 6 – 12 weeks before primary closure. • Gap of more than 6-8 vertebrae, oesophageal replacement

  12. Post operation- early complications • Anastomotic leak , 27%, 24 – 72hrs • Anastomotic stricture • Recurrent tracheo oesophageal fistula

  13. Late complications • Tracheomalacia • Gastro oesophageal reflux • Respiratory problems • Motility disorders • Growth

  14. Research • Family study – broad spectrum • Relatives of TOF have these anomalies (genetic factor) • Range of medical problems ie dysmotility, reflux –family have these. (Genetic story to investigate) • Vitamin A, Adriamycin (cancer drug)

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