Mifepriston in emergency contraception. V.N.Prilepskay ., А.А. Kuzemin , Т.А. Nazarenko , Т.М. Astakhova Research Centre of Obstetrics , Gynecology & Perinatology Moscow,Russia. М ifepriston. Synthetic steroid , derivative of nortetisteron with antigestagen activity .
Mifepriston in emergencycontraception
Research Centre of Obstetrics, Gynecology & Perinatology Moscow,Russia
Synthetic steroid, derivative of nortetisteron with antigestagen activity.
Main indication for the use in medical abortion
V.N.Prilepskay., А.А.Kuzemin,Т.А.Nazarenko, Т.М.Astakhova2004.
Clinical trials os these indications were carried out in Russia for the first time at the Research center of Obstetrics, Gynecology and Perinatology of the Russian Academy of Medical Sciences.
Coordinator of the trial was academican Vladimir I.Kulakov
A total of 30 women were investigated.
Age from 18 till 33 лет, mean age 23,8+/-1,7.
А) verified by ultrasonography
В) verified by tests for Chorionic gonadotropin in blood plasma
General criterion of is a number of pregnancies/number of women using Mifepriston
(Randomized double blind study in 15 family planning clinics in 10 сountries (4136 healthy women with regylar menstrual cycle)).
Helene von Hertzen et al. Lancet 2002, 360:1803-10
150 patients in each group
Most typical side effect (in 6 patiens, 20 %) –is menstrual disoders during the first two cycles after the witgdrawal of it.