Chromosomal Karyotypes. Dawn Adams Cytogenetics CDC’s 2003 Science Ambassador Program. Overview. I. Chromosomes A. Definition B. Structure C. Identification II. Karyotypes A. Definition B. Methods C. Staining D. Importance. Chromosomes. Definition
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CDC’s 2003 Science Ambassador Program
Example - 1q2.4
Each arm divided into sub-regions and identified by a number
Each sub-region divided into bands identified with a number
Chromosome is identified with a number ranging 1-22, or X and Y
1 2 3 4 5
6 7 8 9 10 11 12
13 14 15 16 17 18
19 20 21 22 X Y
Fetal samples for karyotypes are commonly obtained in two ways
Banding patterns can be visually identified on chromosomes after staining.
Karyotypes show the chromosomal makeup of an individual. Knowing the number of chromosomes is essential for identifying chromosomal variations that cause genetic disorders.