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Disease Progression in Multiple Sclerosis: Predicting Outcomes

Disease Progression in Multiple Sclerosis: Predicting Outcomes. Learning Objective. Disease Progression vs Suboptimal Treatment Response. How Do We Assess Disease Activity?. Patient Presentation. Patient Presentation (cont). Debra’s 2009 Brain MRI (FLAIR). Debra’s 2009 Cervical Spine MRI.

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Disease Progression in Multiple Sclerosis: Predicting Outcomes

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  1. Disease Progression in Multiple Sclerosis: Predicting Outcomes

  2. Learning Objective

  3. Disease Progression vs Suboptimal Treatment Response

  4. How Do We Assess Disease Activity?

  5. Patient Presentation

  6. Patient Presentation (cont)

  7. Debra’s 2009 Brain MRI (FLAIR)

  8. Debra’s 2009 Cervical Spine MRI

  9. Patient Presentation (cont)

  10. Risk Factors for Progression

  11. Debra’s Risk Factors

  12. How Do We Measure Disease Progression?

  13. Clinical Disease: Relapses

  14. Clinical Disease: Disability

  15. In Your Opinion, What Is The Best Way to Assess Disease Activity In Patients With MS?

  16. Long-term Outcomes: CIS and MRI

  17. Long-term Outcomes: Risk Factors

  18. Long-term Outcomes: Disability

  19. Debra’s 2009 FLAIR MRI

  20. Debra’s 2010 FLAIR MRI (Postpartum)

  21. MRI Assessment

  22. Suboptimal Response Despite DMT

  23. At What Disease Activity Threshold Do You Change a DMT?

  24. Challenge of Switching Medications

  25. Abbreviations

  26. References

  27. References (cont)

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