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Margaretha Haugen Division of Environmental Medicine, NIPH

EUCCONET International Workshop Bristol, 18 th and 19 th October. Brief description of maternal/dietary parameters recorded. Margaretha Haugen Division of Environmental Medicine, NIPH. In Norway. All citizens have a unique identity number National Population Registry

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Margaretha Haugen Division of Environmental Medicine, NIPH

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  1. EUCCONET International Workshop Bristol, 18th and 19th October Brief description of maternal/dietary parameters recorded Margaretha Haugen Division of Environmental Medicine, NIPH

  2. In Norway • All citizens have a unique identity number • National Population Registry • Medical Birth Registry of Norway • Centralised ultrasound scans • 98% of all pregnant women have scan in week 17/18 at birthing hospital

  3. MoBa - recruitment • Pregnant women invited in week 15 • Informed consent from both mother and father • No exclusion criteria (apart from language) • Recruitment June 1999-December 2008 • Total response rate = 39%

  4. MoBa - participation

  5. Dietary assessment in MoBa Ultrasoundweek 17 week 22 Dietary supplements, caffeine and alcohol QI QII FFQ, supplements during first 4-5 months of pregnancy Mother week 30 Fish and game intake, supplements, caffeine, alcohol and sweet drinks QIII 6 months Breastfeeding, weaning foods and supplements QIV 18 months The child's intake of milk, bread, dinners, drinks and cereals/porridge. Supplements QV 3 years Child The child's intake of milk, bread, dinners, drinks. Supplements QVI 7 years The child's intake of milk, bread, dinners, drinks. Supplements QVII 8 years QVIII No diet questions 14 years Plan to assess total diet

  6. Dietary assessment in MoBa – in pregnancy • 340 questions, 40 groups of questions • 255 foods and dishes • 14 pages Meltzer et al., “Methodologcial challenges when monitoring the diet of pregnant women in a large study: experiences from the Norwegian Mother and Child Cohort Study” MCN; 2008: 4:14-27

  7. Validation study, MoBa FFQ n=119, 4-d FD + biomarkers in blood and in 24-hurine + motion sensor

  8. Validation study, MoBa FFQ • Acceptable agreement between the FFQ and the FD for all nutrients and major foods • Biomarkers confirmed that the FFQ estimates were valid for fruit, juice, vegetables, tea, milk/dairy foods, protein, vitamin D, folate, iodine, n-3 fatty acids • The MoBa FFQ provide valid estimates of nutrients supplied by dietary supplements Brantsæter et al., Maternal and Child Nutrition, 2008 Brantsæter et al, Annals of Nutrition and Metabolism, 2008 Brantsæter et al., Public Health Nutrition, 2007

  9. Use of dietary supplements in MoBa • 82 % of the women register use of one or more • dietary supplement Haugen et al. Ann Nutr and Metab 2008.

  10. RESULTS Birth weight (mean and 95%CI) by categories of total seafood intake in 62099 women in the Norwegian Mother and Child Cohort Study Conclusion: a consistent increase in infant birth weight and head circumference with increasing maternal seafood consumption, this association was mainly driven by lean fish. Brantsæter et al. Br J Nutr. 2011

  11. Dietary assessment in MoBa – children • 6 months: retrospective reporting • Supplementation during the first week of life • What kind of milk the baby had received at each month since birth to estimate duration and intensity of breastfeeding • Weaning foods and at which month they were introduced • Dietary supplements supplied to the baby

  12. Breastfeeding, MoBa women Häggkvist et al. Public Health Nutr. 2010

  13. Dietary assessment in MoBa – children • Eighteen months (Q5): • Breast milk after 6 months of age • Selected foods, drinks and dietary supplements • Three years (Q6), Five years (Q7) • Selected foods, drinks and dietary supplements The questions are not complete for assessing total diet or to estimate intake of energy, nutrient or any daily intakes quantitatively, only to study dietary patterns and distinguish dietary behaviours

  14. Future perspectives To examine longitudinal dietary exposure in relation to health outcomes for the child (weight gain/obesity, developmental milestones, asthma/allergy, cognitive development etc) + Weaning foods and early diet In utero Breast milk +

  15. MoBa continues…… Two new questionnaires are planned: Q-12 years pre-puberty – mental health Q-14 years nutrition – to be completed by the teenager

  16. More information: ww.fhi.no/morogbarn All questionnaires can be downloaded and are translated to English.

  17. The core diet group in MoBa Helle Margrete Meltzer Margaretha Haugen Jan Alexander Anne Lise Brantsæter Bryndis Eva Birgisdottir Helen E Kvalem Hanne Torjusen Helle Knutsen

  18. Collaborators • Epidemiology • Per Magnus • Lill Trogstad • Ronny Myhre • Roy M Nilsen (UiB) • Bo Jacobsson (Gøteborg) • Sven Ove Samuelsen (UiO) • International • Sjurdur Olsen • Inga Thorsdottir • Matt Longnecker • Stephanie London • Anna-Maria Siega-Riz • Cindy Bulik • Michelle Mendez

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