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DEFINITIONS. NAME THAT ANTIGEN. DISEASE ASSOCIATION. KELL SYSTEM. ENZYMES. 1pt. 1 pt. 1 pt. 1pt. 1 pt. 2 pt. 2 pt. 2pt. 2pt. 2 pt. 3 pt. 3 pt. 3 pt. 3 pt. 3 pt. 4 pt. 4 pt. 4pt. 4 pt. 4pt. 5pt. 5 pt. 5 pt. 5 pt. 5 pt.

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DEFINITIONS

NAME THAT

ANTIGEN

DISEASE

ASSOCIATION

KELL

SYSTEM

ENZYMES

1pt

1 pt

1 pt

1pt

1 pt

2 pt

2 pt

2pt

2pt

2 pt

3 pt

3 pt

3 pt

3 pt

3 pt

4 pt

4 pt

4pt

4 pt

4pt

5pt

5 pt

5 pt

5 pt

5 pt



Immunogenicity response.



Low prevalence 10% of the general population.

Low frequency

Low incidence

Familial

Private


DAILY DOUBLE 10% of the general population.

This is a known failure of an antigen-antibody reaction to yield a positive test result as a consequence of antibody excess.


Prozone 10% of the general population.


This is the term for a reaction in which one cell population is agglutinated, but a second cell population remains free.


Mixed-field is agglutinated, but a second cell population remains free.


What term has been used to denote those antibodies which react weakly both when diluted or undiluted, but are present in high concentration.


HTLA react weakly both when diluted or undiluted, but are present in high concentration.

(High Titer, Low Avidity)



Kell immunogenic.



k (Cellano) immunogenic.

Kpb ( Rautenberg)

Jsb (Matthews)



Le the genes c


Anti-Tj the genes a is associated with this blood group system.


P the genes


Name one antigen that is part of the C the genes 4 molecule of complement, and therefore not an intrinsic part of the RBC membrane.

(An example of an HTLA antibody)


Chido or Rodgers the genes


This relatively uncommon antibody is found in up to 80% of patients with infectious mononucleosis.


Anti-i patients with infectious mononucleosis.



Kx Chronic Granulomatous Disease.


The erythrocytes of individuals with this phenotype appear to resist invasion by

Plasmodium vivax.


Fy (a-b-) to resist invasion by


The Donath-Landsteiner antibody that is present in the serum of patients with paroxysmal cold hemoglobinuria (PCH) has this specificity.


Anti-P of patients with paroxysmal cold hemoglobinuria (PCH) has this specificity.


A patient with a of patients with paroxysmal cold hemoglobinuria (PCH) has this specificity.Mycoplasma pneumoniae infection will most likely develop a cold autoantibody with this specificity.


Anti-I of patients with paroxysmal cold hemoglobinuria (PCH) has this specificity.



AHG of testing.


Give two reasons a patient who had anti-K two years ago now appears to be compatible with two random donor units of red blood cells.


  • Both units are K negative. appears to be compatible with two random donor units of red blood cells.

  • The anti-K titer is too low to be detected.


Name three pairs of antithetical antigens at the Kell locus. appears to be compatible with two random donor units of red blood cells.


  • K and k (Kell and Cellano) appears to be compatible with two random donor units of red blood cells.

  • Kpa and Kpb (Penny and Rautenberg)

  • Jsa and Jsb (Sutter and Matthews)


Individuals of the Kell null phenotype may only be transfused with RBCs from other Kell null individuals because their plasma contains this antibody.


Anti-K transfused with RBCs from other Kell null individuals because their plasma contains this antibody.u



9 this many random donors out of ten.



Ficin Banking.



Papaya Banking.



Kidd, Lewis , Rh, Ii, P, ABO Banking.

(Kidd Lewis has Ripples In his Pecs and Abs.)


DAILY DOUBLE Banking.

Name 5 blood group antigens that are adversely affected by proteolytic substances.


MNS, Fy, Xg Banking.a

(Many New Soldiers are destroyed in the Field by eXplosions.)

Note: Sometimes Kell (Many New Soldiers are Killed in the Field by eXplosions)




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