DEFINITIONS. NAME THAT ANTIGEN. DISEASE ASSOCIATION. KELL SYSTEM. ENZYMES. 1pt. 1 pt. 1 pt. 1pt. 1 pt. 2 pt. 2 pt. 2pt. 2pt. 2 pt. 3 pt. 3 pt. 3 pt. 3 pt. 3 pt. 4 pt. 4 pt. 4pt. 4 pt. 4pt. 5pt. 5 pt. 5 pt. 5 pt. 5 pt.
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This is the ability of an antigen to stimulate an antibody response.
This is the term for antigens that are present in less than 10% of the general population.
This is a known failure of an antigen-antibody reaction to yield a positive test result as a consequence of antibody excess.
This is the term for a reaction in which one cell population is agglutinated, but a second cell population remains free.
What term has been used to denote those antibodies which react weakly both when diluted or undiluted, but are present in high concentration.
(High Titer, Low Avidity)
After the ABO and Rh antigens, this antigen is the most immunogenic.
Name an antigen in the Kell system that is high prevalence.
Kpb ( Rautenberg)
This antigen is formed by a non-secretor who has inherited the genes lele.
Anti-Tja is associated with this blood group system.
Name one antigen that is part of the C4 molecule of complement, and therefore not an intrinsic part of the RBC membrane.
(An example of an HTLA antibody)
Chido or Rodgers
This relatively uncommon antibody is found in up to 80% of patients with infectious mononucleosis.
This antigen, related to the Kell system, is associated with Chronic Granulomatous Disease.
The erythrocytes of individuals with this phenotype appear to resist invasion by
The Donath-Landsteiner antibody that is present in the serum of patients with paroxysmal cold hemoglobinuria (PCH) has this specificity.
A patient with a Mycoplasma pneumoniae infection will most likely develop a cold autoantibody with this specificity.
Antibodies of the Kell system generally react at this phase of testing.
Give two reasons a patient who had anti-K two years ago now appears to be compatible with two random donor units of red blood cells.
Name three pairs of antithetical antigens at the Kell locus.
Individuals of the Kell null phenotype may only be transfused with RBCs from other Kell null individuals because their plasma contains this antibody.
A person with anti-K will be compatible with approximately this many random donors out of ten.
This enzyme is the most commonly used in routine Blood Banking.
Papain is derived from this plant.
Name 5 blood group antigens that are enhanced by enzymes.
Kidd, Lewis , Rh, Ii, P, ABO
(Kidd Lewis has Ripples In his Pecs and Abs.)
Name 5 blood group antigens that are adversely affected by proteolytic substances.
MNS, Fy, Xga
(Many New Soldiers are destroyed in the Field by eXplosions.)
Note: Sometimes Kell (Many New Soldiers are Killed in the Field by eXplosions)
These antigens of the Duffy system are enzyme resistant.
Fy3, Fy5 (and Fy4)