番禺的各位同行 : 早 上 好！. SIRS , Sepsis MODS & Shock 全身炎症反应综合征 脓毒症 , MODS 和休克. 曾 其 毅. A clinician, armed with the sepsis bundles, attacks the three heads of severe sepsis: hypotension, hypoperfusion and organ dysfunction. Crit Care Med 2004; 320(Suppl):S595-S597.
SIRS , SepsisMODS & Shock , MODS
What is SIRS
What is sepsis
SIRS / Sepsis
Balance between pro- and anti-inflammatory mediators
pro-inflammatory anti-inflammatoryTNF-, IL-1, IFN-, LT-, IL-1RA, sTNFR, sIL-1RIL-2, IL-8, IL-12,IL-18, C TGF-, IL-4, IL-6, IL-10LTB4, PAF, Kinine, NO IL-11, IL-13, PGE2, G-CSFGM-CSF, chemokine, MIF antioxidants, IFN-a
Examples of high and low capillary density. The capillary density was calculated similar to the technique of De Backer et al.1 A grid of equidistant vertical and horizontal lines was superimposed on the image. The vessel density was calculated as the number of small
vessels (20 m) intersecting the lines of the grid divided by the total length of the lines yielding the number of small vessels per millimeter. The image in A represents a high capillary density, and the image in B represents a low capillary density. Real-time video sequences of orthogonal polarization spectral imaging in severe sepsis and septic shock are available from the authors through a file download.
I () () XCT
R () , WBCCRPPCT
O () PaO2/FIO2
How to treat sepsis
Cost / effect
Cost = !!