1 / 8

1Quiz #9 for 10:30

1Quiz #9 for 10:30. Choose two of the following false or misleading statements and make the appropriate corrections. Be sure to write the number of the questions you choose.

gant
Download Presentation

1Quiz #9 for 10:30

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. 1Quiz #9 for 10:30 Choose two of the following false or misleading statements and make the appropriate corrections. Be sure to write the number of the questions you choose. • Thyroid hormones are stored in intracellularly in secretory vesicles before they are release from a stimulated follicular endocrine cell. • In the form of thyrotoxicosis called Grave’s Disease, excessive secretion of TSH stimulates thyroid follicular cells to release too much of the thyroid hormones into the bloodstream. • Basal levels of epinephrine must be present so that cell can be appropriately responsive to thyroid hormone. • All hormones released from the pituitary are produced by cell bodies in the hypothalamus. Note: next Monday’s quiz will include material from Frog Reflex Lab

  2. 1Quiz #9 for 11:30 Choose two of the following false or misleading statements and make the appropriate corrections. Be sure to write the number of the questions you choose. • Thyroid hormones are stored in intracellularly in secretory vesicles before they are release from a stimulated follicular endocrine cell. • In the form of thyrotoxicosis called Grave’s Disease, excessive secretion of TSH stimulates thyroid follicular cells to release too much of the thyroid hormones into the bloodstream. • Basal levels of epinephrine must be present so that cell can be appropriately respond to thyroid hormone. • Goiters are enlarged thyroid glands that occur because of excess stimulation by thyroid hormone. Note: next Monday’s quiz will include material from Frog Reflex Lab.

  3. Age 16 33 52 S 1 Another Endocrine Disorder

  4. Disorder =Acromegaly S 2 • Excessive growth of bones and soft tissues of face and hands, and feet. • Hypersecretion of Growth Hormone from adenohypophysis or ectopic tumor in adults • Treatment? • Somatostatin analogs • GH receptor blockers • Transphenoidal resection/ablation with focal radiation GHRH SS GH Compare to Pituitary Gigantism IGF-1 Acromegaly in Merck Manual

  5. S 3 Classification of Endocrine Disorders • Hypersecretion • Primary • Secondary • Hyposecretion • Primary • Secondary • Hyper-responsive target • Hypo-responsive target Try to classify: Endemic GoiterGrave’s DiseaseAcromegaly Diabetes mellitus Type 1Diabetes mellitus Type 2

  6. Lab Next Week:Case Studies in Endocrinology Look at the on-line Merck Manual before your lab day. http://www.merckmanuals.com/professional/index.html Follow Link to Endocrine and Metabolic Disorders

  7. STRESS Cytokines fromimmune cells CRH from Hypothalamus ACTH from Ant. Pit Mobilize fuel from muscle & adipose tissueSuppress non-essential functions (reproduction & growth)Suppress inflammatory &immune responsesPotentiates response to EPI (vascular smooth muscle) S 5 Physical traumaProlonged exposure to coldProlonged intense exerciseInfectionSleep deprivationPainFrightEmotional distress Vasopressin Clinical example: treatment of chronic inflammation (e.g. arthritis) can lead to Cushing’s Syndrome! ⇧Cortisol secretion from Adrenal Cortex Cushing’s Syndrome Excess Cortisol from 1) adrenal cortex tumor (primary) or 2) hypersecretion of ACTH from anterior pituitary (secondary)

  8. S 6 Why are NSAIDs preferable to Glucocorticoids for treating inflammation andarthritis? Consider the HPA axis and the effects of long-term dosing with cortisol on ACTH secretion and the Adrenal Cortex.

More Related