Effects of probiotics on child growth a systematic review
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EFFECTS OF PROBIOTICS ON CHILD GROWTH - A Systematic Review . By : Onubi , Ojochenemi Joy MBBS, MSc International Health and Management. OUTLINE. Introduction Aim and Objectives Methods Results Conclusion and Recommendations References. INTRODUCTION.

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EFFECTS OF PROBIOTICS ON CHILD GROWTH - A Systematic Review

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Effects of probiotics on child growth a systematic review

EFFECTS OF PROBIOTICS ON CHILD GROWTH - A Systematic Review

By: Onubi, Ojochenemi Joy

MBBS, MSc International Health and Management


Outline

OUTLINE

  • Introduction

  • Aim and Objectives

  • Methods

  • Results

  • Conclusion and Recommendations

  • References


Introduction

INTRODUCTION

  • Optimal child growth is important for children reach their full cognitive and social potential

  • Under-nutrition in children is manifested as underweight, stunting and wasting.

  • In 2011, the WHO estimated that globally,

    25% of under-five children are under-nourished

    18% are under-weight while 28% are stunted. The majority of these children reside in Africa and Asia .


Causes and consequences of under nutrition

CAUSES AND CONSEQUENCES OF UNDER-NUTRITION


Under nutrition and mdgs

UNDER-NUTRITION AND MDGs

  • MDG 1: Eradicate extreme poverty and hunger – some improvement

  • MDGs 2, 3, 4, 5, 6

  • In Guatemala and Zimbabwe, food supplementation during early childhood improved schooling in men and women

  • height-for-age: 1 Z score was associated with an 8% increase in income in Brazil and Guatemala as well as with an increase of 0·27 household assets in India


Probiotics

PROBIOTICS

  • Probiotics are live micro-organisms which confer a health benefit on the host when they are consumed in adequate amounts.

  • The dietary intake of probiotics may lead to improved growth in children and therefore help in reducing the prevalence and magnitude of under-nutrition.


Probiotics and growth

PROBIOTICS AND GROWTH

PROBIOTICS

GROWTH


Aim and objectives

AIM AND OBJECTIVES

  • Aim: To systematically review the available evidence on the effects of probiotics on the growth of children.

  • Objectives:

  • i) To determine the effect of probiotics on the growth of healthy young children

  • ii) To determine the effect of probiotics on the growth of undernourished children


Methods

METHODS

  • Three electronic databases were searched using inclusion and exclusion criteria MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials

  • Reference lists were also searched.

  • Outcome measure was change in growth- weight, height/length

  • Analysis was by a narrative synthesis of results


Results

RESULTS

  • Eleven studies were included in the review

    - Seven healthy children studies

    - four under-nourished children studies

  • The studies varied in type and quantity of probiotics, duration of interventions, characteristics of participants and units of outcome measurement.

  • Four studies found that probiotics lead to an increase in growth of children


Figure 1 effects of probiotics on weight gain of healthy children

Figure 1: Effects of Probiotics on weight gain of healthy children


Figure 2 probiotics and weight gain in undernourished children

Figure 2: Probiotics and weight gain in undernourished children


Results contd

RESULTS Contd

  • Consistent improvement in growth of children in low income settings

  • Availability and cost: Use of locally sourced, cheap probiotic substance

  • Acceptance

  • Adverse effects


Conclusion and recommendations

CONCLUSION AND RECOMMENDATIONS

  • The dietary intake of probiotics seems to be effective in improving the growth of children in developing countries.

  • May contribute to the pace of achieving MDGs

  • However, there is a need for more quality research studies on the effects of probiotics on growth- different probiotics, age groups, settings, explore local sources


R eferences

REFERENCES

  • Thomas DW, Greer FR, Bhatia JJS, Abrams SA, Daniels SR, Schneider MB, et al... Clinical report - Probiotics and prebiotics in pediatrics. Pediatrics 2010 December 2010;126(6):1217-1231

  • Braegger C, Chmielewska A, Decsi T, Kolacek S, Mihatsch W, Moreno L, et al... Supplementation of infant formula with probiotics and/or prebiotics: A systematic review and comment by the ESPGHAN committee on nutrition. J PediatrGastroenterolNutr 2011 February 2011;52(2):238-250

  • Steenhout PG, Rochat F, Hager C. The effect of bifidobacteriumlactis on the growth of infants: A pooled analysis of randomized controlled studies. Annals of Nutrition and Metabolism 2009 December 2009;55(4):334-340.


Effects of probiotics on child growth a systematic review

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