(A) Rotarod test. Day 2. Day 3. Day 4. Day 5. Day 1. Test phase Max :32 rpm Acceleration mode (6 repetitions). Training phase 120 s at 5 rpm Constant mode (5 repetitions). (B) MBx and electrophysiology. Week 7. Week 15. Week 23. MBx -16th week. MBx – 24th Week.
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Max :32 rpm
120 s at 5 rpm
(B) MBx and electrophysiology
MBx – 24th
Supplementary Figure 1
Week 9, 16 & 23
Schematic time scale of experiments. A: Rotarod. B: Muscle biopsy (MBx) and electrophysiology. rpm = rotations per minute