Supplementary Figure
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Supplementary Figure 3. Schematic representation of effect of DFMO on ODC pathway. Polyamine Catabolism. Normal Pancreas. Kras. β -catenin. p16. C- Myc. P21 p27. PanIN-1,2,3 Carcinoma. DFMO. ODC. OAZ. Polyamines.

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Kras

Supplementary Figure 3. Schematic representation of effect of DFMO on ODC pathway

Polyamine Catabolism

Normal Pancreas

Kras

β-catenin

p16

C-Myc

P21

p27

PanIN-1,2,3

Carcinoma

DFMO

ODC

OAZ

Polyamines


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