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Blood. Components of Blood. Whole blood RBCs WBCs Platelets: cell fragments that aid in clotting Plasma 90% water (allows materials to dissolve) Amino acids, glucose, hormones, vitamins, salts, waste Concentrations allows diffusion in/out of blood stream. Red Blood Cells.

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components of blood
Components of Blood
  • Whole blood
    • RBCs
    • WBCs
    • Platelets: cell fragments that aid in clotting
  • Plasma
    • 90% water (allows materials to dissolve)
    • Amino acids, glucose, hormones, vitamins, salts, waste
    • Concentrations allows diffusion in/out of blood stream
red blood cells
Red Blood Cells
  • Job: Transport O2 to cells
  • Produced from stem cells in bone marrow
  • Dead RBC’s filtered by liver & spleen and combine with poop
white blood cells
White Blood Cells
  • Job: Kill foreign invaders & dead cells
  • Able to move through tissue to swallow invaders
platelets
Platelets
  • Job: Help form clots to stop bleeding
  • Proteins form a web to trap cells & platelets
abo blood groups
ABO Blood Groups
  • Antigens:
    • Proteins on RBC’s that determine your blood type
    • Help to identify cells as foreign or natural
    • Analogy: Antigens are like jersey’s
  • Antibodies:
    • Part of your immune system
    • Float freely in plasma
    • Job: attack foreign antigens
group a blood

What would happen if a virus with B antigens entered your blood?

Your B antibodies will attack and kill this virus.

Group A blood

Vein

  • RBC’s have the A antigens on their surface
  • B antibodies in your plasma
    • only attack invaders with B antigens

B antibody

B antibody

B antibody

B antibody

group a blood1

Your B antibodies will attack, and cause clots to form. This person will die.

What would happen if you gave this person type B blood?

Group A blood

Vein

  • RBC’s have the A antigens on their surface
  • B antibodies in your plasma
    • only attack invaders with B antigens

B antibody

B antibody

B antibody

B antibody

group b blood

What would happen if a virus with A antigens invaded your blood?

The A antibodies would attack and kill the virus.

Group B blood

Vein

  • RBC’s have B antigens on their surface
  • A antibodies in your blood plasma
    • only attack invaders with A antigens

A antibody

A antibody

A antibody

A antibody

group b blood1

Their A antibodies would attack the donated blood, causing blood clots. This person would die.

What would happen if this person was given type A blood during a transfusion?

Group B blood

Vein

A antibody

  • RBC’s have B antigens on their surface
  • A antibodies in your blood plasma
    • only attack invaders with A antigens

A antibody

A antibody

A antibody

group ab blood

What would happen if this person was invaded by the viruses below?

They do not have antibodies to attack these viruses.

Group AB blood

Vein

  • RBC’s have both A & B antigens on their surface
  • Neither A or B antibodies in your blood plasma

Can you predict the antibodies they will have?

group ab blood1

Nothing bad would happen. They have no antibodies to attack this blood.

Nothing bad would happen. They have no antibodies to attack this blood.

What would happen if you gave this person type B blood?

What would happen if you gave this person type A blood?

Group AB blood

Vein

  • RBC’s have both A & B antigens on their surface
  • Neither A or B antibodies in your blood plasma
group o blood

The antibodies would attack and kill the viruses.

What would happen if this person was invaded by the viruses below?

Group O blood

Vein

  • Neither A or B antigens on the surface of your RBCs
  • Both A & B antibodies in your plasma
    • will attack invaders with A or B antigens

A antibody

A antibody

B antibody

B antibody

Can you predict the antibodies they will have?

group o blood1

The A antibodies will attack, causing blood clots. This person will die.

What would happen if you gave this person type A blood?

Group O blood

Vein

  • Neither A or B antigens on the surface of your RBCs
  • Both A & B antibodies in your plasma
    • will attack invaders with A or B antigens

A antibody

A antibody

B antibody

B antibody

group o blood2

The B antibodies will attack, causing blood clots. This person will die.

What would happen if you gave this person type B blood?

Group O blood

Vein

  • Neither A or B antigens on the surface of your RBCs
  • Both A & B antibodies in your plasma
    • will attack invaders with A or B antigens

A antibody

A antibody

B antibody

B antibody

group o blood3

Both the A and B antibodies will attack, causing blood clots. This person will die.

What would happen if you gave this person type AB blood?

Group O blood

Vein

  • Neither A or B antigens on the surface of your RBCs
  • Both A & B antibodies in your plasma
    • will attack invaders with A or B antigens

A antibody

A antibody

B antibody

B antibody

slide26

If you have type A blood, can you receive:

Type A blood?

Type B blood?

Type AB blood?

Type O blood?

Yes

No

No

Yes

B antibodies will attack any blood with B antigens.

slide27

If you have type B blood, can you receive:

Type B blood?

Type A blood?

Type AB blood?

Type O blood?

Yes

No

No

Yes

A antibodies will attack any blood with A antigens.

slide28

If you have type AB blood, can you receive:

Type AB blood?

Type A blood?

Type B blood?

Type O blood?

Yes

Yes

Yes

Yes

They have neither A nor B antibodies.

slide29

If you have type O blood, can you receive:

Type O blood?

Type A blood?

Type B blood?

Type AB blood?

Yes

No

No

No

A antibodies will attack any blood with A antigens.

B antibodies will attack any blood with B antigens.

rh factors
Rh Factors
  • If Rh+
    • Cells contain the Rh antigen
    • Can receive Rh+ or Rh- blood
  • If Rh-
    • Cells lack the Rh antigen
    • Plasma contains Rh antibody
    • Only receive Rh- blood
francis was just in a bad accident and lost a lot of blood he is blood type b can you help save him
Francis was just in a bad accident and lost a lot of blood. He is blood type B+. Can you help save him?
blood type b
Blood type B+

Antigens: Which does he have?

A

B

Rh

Antibodies: Which does he have?

A

B

Rh

francis has b blood type because of the b and rh antigens if he is given b blood in a transfusion
Francis has B+ blood type because of the B and Rh antigens. If he is given B+ blood in a transfusion…

Will his antibodies attack this blood?

No. His A antibodies only attack A antigens.

Can he receive B+ blood?

Yes.

Vein

A antibody

A antibody

A antibody

slide36

Francis has B+ blood type because of the B and Rh antigens. If he is given B- blood in a transfusion…

Will his antibodies attack this blood?

No. His A antibodies only attack A antigens.

Can he receive B- blood?

Yes.

Vein

A antibody

A antibody

A antibody

slide37

Francis has B+ blood type because of the B and Rh antigens. If he is given A+ blood in a transfusion…

Will his antibodies attack this blood?

Yes. His A antibodies will attack the A antigens.

Can he receive A+ blood?

No.

Agglutination: clumping of the blood

Vein

A antibody

A antibody

A antibody

francis has b blood type because of the b and rh antigens if he is given a blood in a transfusion
Francis has B+ blood type because of the B and Rh antigens. If he is given A- blood in a transfusion…

Will his antibodies attack this blood?

Yes. His A antibodies will attack the A antigens.

Can he receive A- blood?

No.

Agglutination: clumping of the blood

Vein

A antibody

A antibody

A antibody

francis has b blood type because of the b and rh antigens if he is given ab blood in a transfusion
Francis has B+ blood type because of the B and Rh antigens. If he is given AB+ blood in a transfusion…

Will his antibodies attack this blood?

Yes. His A antibodies will attack the A antigens.

Can he receive AB+ blood?

No.

Agglutination: clumping of the blood

Vein

A antibody

A antibody

A antibody

francis has b blood type because of the b and rh antigens if he is given ab blood in a transfusion1
Francis has B+ blood type because of the B and Rh antigens. If he is given AB- blood in a transfusion…

Will his antibodies attack this blood?

Yes. His A antibodies will attack the A antigens.

Can he receive AB- blood?

No.

Agglutination: clumping of the blood

Vein

A antibody

A antibody

A antibody

francis has b blood type because of the b and rh antigens if he is given o blood in a transfusion
Francis has B+ blood type because of the B and Rh antigens. If he is given O+ blood in a transfusion…

Will his antibodies attack this blood?

No. His A antibodies only attack A antigens.

Can he receive O+ blood?

Yes.

Vein

A antibody

A antibody

A antibody

francis has b blood type because of the b and rh antigens if he is given o blood in a transfusion1
Francis has B+ blood type because of the B and Rh antigens. If he is given O- blood in a transfusion…

Will his antibodies attack this blood?

No. His A antibodies only attack A antigens.

Can he receive O- blood?

Yes.

Vein

A antibody

A antibody

A antibody

slide43
Sebastian was just involved in an accident at work and lost a lot of blood. He is blood type A-. Can you help save him?
blood type a
Blood type A-

Antigens: Which does he have?

A

B

Rh

Antibodies: Which does he have?

A

B

Rh

sebastian has a blood type because of the a antigen if he is given a blood in a transfusion
Sebastian has A- blood type because of the A antigen. If he is given A- blood in a transfusion…

Will his antibodies attack this blood?

No. His B and Rh antibodies only attack B and Rh antigens.

Can he receive A- blood?

Yes.

Vein

B antibody

Rh antibody

Rh antibody

B antibody

B antibody

Rh antibody

sebastian has a blood type because of the a antigen if he is given a blood in a transfusion1
Sebastian has A- blood type because of the A antigen. If he is given A+ blood in a transfusion…

Will his antibodies attack this blood?

Yes. His Rh antibodies will attack the donated Rh antigens.

Can he receive A+ blood?

No.

Agglutination: clumping of the blood

Vein

B antibody

Rh antibody

Rh antibody

B antibody

B antibody

Rh antibody

sebastian has a blood type because of the a antigen if he is given b blood in a transfusion
Sebastian has A- blood type because of the A antigen. If he is given B- blood in a transfusion…

Will his antibodies attack this blood?

Yes. His B antibodies will attack the donated B antigens.

Can he receive B- blood?

No.

Agglutination: clumping of the blood

Vein

B antibody

Rh antibody

Rh antibody

B antibody

B antibody

Rh antibody

sebastian has a blood type because of the a antigen if he is given b blood in a transfusion1
Sebastian has A- blood type because of the A antigen. If he is given B+ blood in a transfusion…

Will his antibodies attack this blood?

Yes. Both his B and Rh antibodies will attack the donated B an Rh antigens.

Can he receive B+ blood?

No.

Agglutination: clumping of the blood

Vein

B antibody

Rh antibody

Rh antibody

B antibody

B antibody

Rh antibody

sebastian has a blood type because of the a antigen if he is given ab blood in a transfusion
Sebastian has A- blood type because of the A antigen. If he is given AB- blood in a transfusion…

Will his antibodies attack this blood?

Yes. His B antibodies will attack the donated B antigens.

Can he receive AB- blood?

No.

Agglutination: clumping of the blood

Vein

B antibody

Rh antibody

Rh antibody

B antibody

B antibody

Rh antibody

sebastian has a blood type because of the a antigen if he is given ab blood in a transfusion1
Sebastian has A- blood type because of the A antigen. If he is given AB+ blood in a transfusion…

Will his antibodies attack this blood?

Yes. Both his B and Rh antibodies will attack the donated B and Rh antigens.

Can he receive AB+ blood?

No.

Agglutination: clumping of the blood

Vein

B antibody

Rh antibody

Rh antibody

B antibody

B antibody

Rh antibody

sebastian has a blood type because of the a antigen if he is given o blood in a transfusion
Sebastian has A- blood type because of the A antigen. If he is given O+ blood in a transfusion…

Will his antibodies attack this blood?

Yes. His Rh antibodies will attack the donated Rh antigens.

Can he receive O+ blood?

No.

Agglutination: clumping of the blood

Vein

B antibody

Rh antibody

Rh antibody

B antibody

B antibody

Rh antibody

sebastian has a blood type because of the a antigen if he is given o blood in a transfusion1
Sebastian has A- blood type because of the A antigen. If he is given O- blood in a transfusion…

Will his antibodies attack this blood?

No. His A antibodies only attack A antigens.

Can he receive O- blood?

Yes.

Vein

B antibody

Rh antibody

Rh antibody

B antibody

B antibody

Rh antibody

blood type ab
Blood type AB+

Antigens: Which does they have?

A

B

Rh

Antibodies: Which does they have?

A

B

Rh

blood type o
Blood type O+

Antigens: Which does they have?

A

B

Rh

Antibodies: Which does they have?

A

B

Rh

blood type ab1
Blood type AB-

Antigens: Which does they have?

A

B

Rh

Antibodies: Which does they have?

A

B

Rh

blood type b1
Blood type B+

Antigens: Which does they have?

A

B

Rh

Antibodies: Which does they have?

A

B

Rh

blood type o1
Blood type O-

Antigens: Which does they have?

A

B

Rh

Antibodies: Which does they have?

A

B

Rh

1 can this work
1) Can this work?
  • Acceptor

O-

  • Donor
  • AB-

No! The acceptor has A & B

antibodies. Their antibodies

would attack the A & B antigens

of the donated blood.

2 can this work
2) Can this work?
  • Acceptor

A+

  • Donor
  • A-

Yes! The acceptor only has

Rh antibodies. Since the donated

blood has no Rh antigens,

this is safe.

3 can this work
3) Can this work?
  • Acceptor

AB-

  • Donor
  • B-

Yes! The acceptor has the Rh

antibodies. There are no Rh antigens

on the donated blood.

kobe kuiz
Kobe Kuiz
  • What are the components found inside blood?
  • What are the ingredients of plasma?
  • What is the purpose/function of RBCs?
  • Which part of blood stop bleeding when cut?
  • What do antibodies bind with?
  • If a person has type AB-, which antigens do they possess? Which antibodies?
  • If a person has type O+, which antigens do they possess? Which antibodies?
  • If a person is type A-, list all the blood types this person can receive in a transfusion.
  • If a person is type O-, list all the blood types this person can receive in a transfusion.
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