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Welcome to Bio181L!. Contemplating the nuts & bolts of Life xVivo’s 3D cell animation (also on TA desktop--Lab01TaoTA => Biovisions => BioVisionsPlayer.swf). About me. Kelsey Berg [email protected] Majors in Physiology/Molecular and Cellular Biology, Minor in Chemistry

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Welcome to bio181l

Welcome to Bio181L!

  • Contemplating the nuts & bolts of Life

  • xVivo’s 3D cell animation

  • (also on TA desktop--Lab01TaoTA => Biovisions => BioVisionsPlayer.swf)


About me

About me...

  • Kelsey Berg

  • [email protected]

  • Majors in Physiology/Molecular and Cellular Biology, Minor in Chemistry

  • From Phoenix, Arizona


What 181l is

What 181L is

  • Thinking, Understanding, Investigating, Evaluating

    • Not arrive, assembly line, leave

  • Not synchronized with most lecture sections, but internally coherent & mutually reinforcing


Science and this course

Science and this course

  • “One of the beautiful things about science is that it allows us to bumble along, getting it wrong time after time, and feeling perfectly fine as long as we learn something each time.”


About you

About you

Last name, First name Section #

Year

Major(s)

Minor(s)

What do you want to do (career)?

Where are you from?

What do you expect from this course?

Anything else that I should know about you (optional)?

  • NOTE: The section dance is now over

    • Once a lab has met, no one can change into it


About the manual

About the manual

  • Reading it will prepare you for class & in-class quizzes

    • Reading prior to 5’ before class will allow you to understand & think about what you’re reading

  • Lays out Philosophy (vii), Learning Goals (ix), expectations (xi)

  • Contains Periodic Table (0-1) and Molecular Basics (0-3), rules of molecule pics (0-5) and a cell (0-7)


181 lab accounts

181 Lab ACCOUNTS

  • http://blc.arizona.edu/courses/181lab

  • Click ‘Create Accounts’

  • Your section number is: XX

  • Bio181L_Go is the best way to do your work. Browser not so much


80 of success is just showing up

80% of success is just showing up*

  • Absences must be excused from from Asya Roberts in BSE109 prior to making up

  • Arriving late is absent. Leaving early is absent.

  • Labs cannot be offered week after they are delivered; Avoid missing a lab

  • Missing 2 labs blows a huge hole in the intellectual content. You may be dropped from the course--excused or otherwise

*--Woody Allen


My webpage

My Webpage

  • Get there via homepage* => Instructors => (Section #)

*http://blc.arizona.edu/courses/181Lab (Lab Man yellow page)


Web page operation

Web page operation


What to expect

What to expect

  • Homework is serious--start early, and work in bursts, with gaps. Generally, 2-3 components/week

  • You will play a major role in experiment, protocol design

    • i.e., you’ll need to know what you’re trying to achieve rather than showing up & following steps. Sometimes, there aren’t any


Policies grading

Policies & Grading

  • Syllabus (Linked on course homepage)

    • Honor code & Plagiarism (Manual, p. xiii)

  • Assignments

    • On-line assessments/tutorials (10%)

    • In-class quizzes (15%)

    • Lab assignments (LABAs--Lab Activity Based Assignments) (50%)

    • Lab Projects & reports (combine to 25%)


The tao of molecules

How?

Why?

the Tao of Molecules

  • How molecules feel & the world they live in


Primary goals

Primary goals

  • Create understanding by observation, reasoning

  • Chemical foundations for the course:

    • Water & its properties

      • non-watery things

    • Know molecules as real & tangible things


Welcome to bio181l

When a journalist asked the great physicist Richard Feynman what single sentence would best encapsulate all science so far if it were to be the sole surviving scrap of all we knew, he replied,“The world is made of atoms.”

From The Secret of Scent, Luca Turin p.28


Atoms they re how life works

Atoms: They’re how life works

  • DNA, RNA: C, H, N, O, P, [Mg++]

  • Carbs: C, H, O

  • Protein: C, H, N, O, (S), (P), [traces]

  • Membranes: C, H, N, O, P, (S)

What cannot be done with assemblages of these atoms* cannot be doneby living organisms, nor their cells, nor their spit, etc.

*OK, fine, there’s the occasional role for Ca++, etc.


Who am i

Who am I?

  • At birth, # protons = # electrons

  • Atoms seek completion, which means outermost electron set = 8 (hydrogen, helium it’s just 2)

Freeman Fig. 2.1a


Coloring your world

Coloring your world


Four views of water

+

O

H

H

+

-

Four views of Water

(There will be a test)

H2O

See lab manual, p. 0-3


Interacting with h2o

Interacting with H2O

To your StructViewers!

Desktop => Bio181L_Go


Doing it

Doing it


Clean up

Clean up!

  • Oil waste in the hood

  • ethanol waste in the sink

  • anything too messy wadded up and discarded


Salting out

It’s a real term; used to refer to a situation where the addition of salt (portable charges) alters the solubility of other molecules in water

Why should this be?

“Salting out”


Evaporation

First things first--what is it? What’s going on in terms of molecules

Experiment: Ethanol and water on your arm: which is cooler & why?

Prediction: based on molecular weight, which should evaporate more quickly--H2O (2 x 1 + 1 x 16) or CH3CH2OH (5 x 1; 2 x 12; 1 x 16)

If not, why not?

Salt--ever tasted your sweat? Or anybody else’s for that matter?

What benefit might there be to adding NaCl to water that you are intending to evaporate?

Evaporation


Some advice

Some advice

http://www.damnlol.com/please-do-me-right-now-224.html


What s an assessor

What’s an Assessor?

=>Chatting<=


What s vocabulary homework

What’s vocabulary homework?

  • EITHER both versions of the crossword exercise

  • OR VocabuWary with a better than threshold score

    • For “Atoms & Molecules”, F12, that’s 60,000

    • Errors count off. Slowness counts off.


Homework due 10 p m before lab

Homework due 10 p.m. before lab

Extensive!

In Depth!

Next week’s quiz will include

Concepts from today

Atom colors

Deducing partial charges (from tutorial)

Manual Ch. 2

  • Assessor: 181 Intro ’12

  • Vocab Atoms/Mols: xWord(x2) or ‘Wary

  • Assessor: Molecular World Tutorial


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