Guidelines for Preventing the Transmission of M. tuberculosis in Health-Care Settings, 2005. Division of Tuberculosis Elimination. December 2006 note: Slide #123 has been edited. Purpose of 2005 Guidelines.
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Division of Tuberculosis Elimination
December 2006note: Slide #123 has been edited.
Potential ongoing transmissionChange in Risk Classifications
LTBI progresses to TB disease in
Risk varies by
Linked to close contact with infectious TB patients during procedures generating aerosols
In hospital TB outbreaks, 1980s–1990s
Administrative Controls Infectiousness (2)
Respiratory ProtectionFundamentals of Infection Control (1)Hierarchy of Infection Control
All settings should perform risk classification as part of risk assessment to determine need for and frequency of an HCW testing program, regardless of likelihood of encountering persons with TB disease.
Risk classification:Medium, with close ongoing surveillance for episodes of transmission
Risk classification:Medium (because of HIV-infected persons)
Risk classification:Low. Could be medium if FB workers are from TB-prevalent countries, or large number of clients are HIV infected.
Factors to consider in TB IC evaluation
TB screening programs provide critical info and consist of
* And other persons who will be tested periodically (i.e., residents and staff of long term–care facilities and correctional settings).
Objectives of contact investigation:
* The percentages in parentheses indicate the minimum allowable laboratory filter efficiency value when challenged with 0.3 μm particles
Infectiousness related to
* If the TST reaction is read as ≥15 mm up to 7 days after placement, the result can be considered positive.
Different cut points used depending on
Used for initial baseline M. tuberculosis testing for those who will be given TST periodically
* Villarino ME, Burman W, Wang YC, Lundergan L, Catanzaro A, Bock N, Jones C, Nolan C. Comparable specificity of 2 commercial tuberculin reagents in persons at low risk for tuberculosis infection. JAMA 1999:281(2):169-71.
The frequency of TB testing for HCWs will be determined by the risk classification for the setting.
For additional information on TB, visit the CDC Division of Tuberculosis Elimination website at