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National Naval Medical Center Directorate for Professional Education Clinical Investigations Department. Introduction to Research at NNMC Marina Borovok, PhD Head of Research Education, Clinical Investigations Department, NNMC
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Introduction to Research at NNMC
Marina Borovok, PhD
Head of Research Education,
Clinical Investigations Department,
“The National Naval Medical Center is an approved provider of continuing nursing education by the Navy Medicine Manpower, Personnel, Training and Education Command, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation.”
This CE/CME activitydoes not have commercial support,and has no conflicts of interest.
3. Know about research support available at NNMC.
Find it !!!"
— Thomas A. Edison
Only through the best available scientific knowledge,
and research-based decision making.
Before you start your research at NNMC, you need to do the following THREE steps:
Step 1: Obtaining a DKO/AKO account
Step 2: Registering with IRBNet, e-portal for publications and protocolsubmission.
Step 3: Completion of CITI training
Go to the DMRN page on DKO/AKO website at https://www.us.army.mil/suite/page/596540
Cue Card Reference:
Login using your AKO/DKO username and password
You are at the DMRN site at https://www.us.army.mil/suite/page/596540
Click on the IRBNet Entry button
Cue Card Reference:
Instructions are at the RCRS website
Please contact Mr. Luis Calvo
Cue Card Reference:
Principal Investigators, Associate Investigators, Research Staff, as well as anyone coming into contact with Human Subjects or involved with the consent process or study design are required to complete this course.
What is next?
The entire research writing process can be divided into easily manageable and clear steps:
STEP 4: Develop a Research Question
Select a topic
Find Sources to support your ideas
STEP 5: Research Protocol Preparation:
Complete Detailed Study Protocol
STEP 6: Submit your proposal via
Funding (if needed)
STEP 4:Good research question: could the "FINER" criteria be applied to it?F- Feasible. Is the question answerable? Do you have access to all the materials you will need to do the study? Do you have access to enough subjects? Will you have enough time and money? Do you have the expertise to do this study or can you collaborate with someone who does?I- Interesting. The question has to be interesting to the investigator, but should also be interesting to others.N- Novel. Has this study been done before? Does it add to the current body of medical knowledge?E- Ethical. Risk/benefit ratio? Can the study be done with a minimal risk? Will an IRB approve the study?R- Relevant. Will it further medical science? Will the results change clinical practice, health policy or point towards further avenues of research?If your question fails on any one of these 5 criteria, it is probably not worth putting much effort into.Additional reading:http://familymed.uthscsa.edu/facultydevelopment/elearning/ResearchQuestions.swf
Choose your mentor, and ask him/her to help.
Web resource :
Literature Search help:
Mr. Fredric Simms, MLS
Phone: (301) 295-0080
E-mail address: [email protected]
Bldg. 1, 1st floor, rm 1633
Statistical Data Analysis help:
Dr. Francois O. Tuamokumo
Phone: (301) 319 8788
Email: [email protected]
Bldg. 1, 4th floor, rm 4342
Finding Sources to support your ideas
Sources come in many forms, such as magazine and journal articles, books, newspapers, videos, films, computer discussion groups, surveys, or interviews.
The trick is to find and then match appropriate, valid sources to your own ideas.
Need help with multiple literature DB?
Please contact Mr. Fredric Simms, MLS
E-mail address: [email protected] Call: 301-295-0080
Human Use Protocol is available on the web at:
These steps will be successful if you worked on the Research Protocol with help of the NNMC specialists (Step 5)
Information on Research Funding is provided
By Dr. Kaminsky (Day 2, Module 9).
Another resource: The Geneva Foundation (slides 65-69)
Cue Card Reference:
You may not begin your research until
you have received
an IRB Approval andApproval Letter
from the Commander, NNMC.
The Walter Reed Army Medical Center (WRAMC) processes are very similar to NNMC, since both centers follow most of the same regulations.
National Naval Medical Center (NNMC) ,
Responsible Conduct of Research Service Sheila Gaines 301-295-6512
Walter Reed Army Medical Center (WRAMC),
Department of Clinical Investigation Verna Parchment 202-782-7828
Malcolm Grow Medical Center (MGMC),
IRB Office Cheryl James 240-857-8216
The Uniformed Services University (USU),
Research Office Maggie Pickerel 301-295-0819
Naval Medical Research Today
886,000 dependents, Navy and Marine Corps retirees, and their
TOTAL: 1,126,600 of a total beneficiary population of almost 3,000,000 people.
NNMC’s goal remains to promote excellence in health care and militarily relevant research and human subject protection.
Our command supports effective and sustainable research, and encourages you to become part of that!
head injury/TBI, stroke,
colon, breast cancer, leukemia and lymphoma,
2009 NNMC Publications Data
Inflammatory Biomarkers in Combat Wound Healing
Hawksworth, Jason S. MD; Stojadinovic,
Alexander MD; Gage, Frederick A.; Tadaki,
Doug K. PhD; Perdue, Philip W. MD;
Forsberg, Jonathan MD; Davis, Thomas A. PhD;
Dunne, James R. MD; Denobile, John W. MD;
Brown, Trevor S. PhD; Elster, Eric A. MD
Annals of Surgery • Volume 250, Number 3, September 2009
There was an article in USA Today about this study: “Navy research could speed troops’ recovery” (see next slide)
Dr. Brooks Cash,
Chief of Gastroenterology at NNMC
Videopresentation by Dr. Cash
Antibiotics and Probiotics in IBS from Brooks Cash, MD
Prosthesis Retention, Serial Debridement, and Antibiotic Bead Use for the Treatment of Infection Following Total Joint Arthroplasty
By LT Scott M. Tintle, MD, MC, USN; LCDR Jonathan A. Forsberg, MD, MC, USN; MAJ Benjamin K. Potter, MD, MC, USA; Richard B. Islinger, MD; LTC Romney C. Andersen, MD, MC, USAORTHOPEDICS 2009; 32:87
List is available on the Intranet at:
Go to the Responsible Conduct of Research Service (RCRS) Intranet site at https://nnmcintra/SiteDirectory/RCRS/default.aspx
and click on Open Protocols
NNMC Research Resources
Responsible Conduct of Research Service (RCRS) – HUMAN SUBJECT PROTECTION,
Stitt library (new name: Darnall Biomedical Learning Resource Center)
Research Protocol/Publication Help,
The Geneva Foundation
Bldg. 1, 4th floor, room 4394
RCRS Intranet https://nnmcintra/SiteDirectory/RCRS/default.aspx
RCRS Internet http://www.bethesda.med.navy.mil/professional/research/Responsible_Conduct/index.aspx
Questions: 301 295-2275
Head of the Clinical Investigation Department:
CAPT Jeffrey Lenert, MD
Research Course: 9 CME/CE, 2 days (0630-1100); 2010: 7/15-16, 9/23-24, 11/1-2. Course PP slide show is available at: https://nnmcintra/SiteDirectory/RCRS/default.aspx
Hands-on Research Preparation Course: April-December, 2010, Th., noon-1400. Information is available on the web at:
PubMed Search Course
Developed and presented by the National Library of Medicine
DATES: Friday, December 10, 2010 at 0900-1115
TIME: 0900 - 1115
LOCATION: NNMC, Bldg 5, room 437
Part I (09:00 – 10:00) Using PubMed (Lecture)
Part II (10:15 – 11:15) Practice with PubMed (hands-on practice)
Course Instructors: Annette Nahin, Margaret McGhee, Elizabeth Frost
PLEASE CONTACT Ms. Ann Holman: 301-319-8411, or via e-mail at
The PubMed links are posted on the Intranet:
RCRS and Stitt Library websites
Stitt Library Website
Workshops are offered all year long at NNMC on a per-request basis.
Please contact our specialists to schedule a workshop
On the web:
Help National Naval Medical Center
a premier research organization
in the Department of Defense.
ICEBERG’s Mentorship Initiative:
Established in 1993 at the request of Madigan Army Medical Center
in Tacoma, WA
Geneva supports research in numerous therapeutic areas to include, but not limited to, the following:
The Grants and Contracts Department (GCD)
works with a variety of investigators on many
different types of awards:
If you are interested in using Geneva\'s services for the preparation of your proposal, please contact the following people:
Mr. Jim Hulbert, Grants and Contracts Manager
Why Partner with Geneva
Turnitin is a Plagiarism Prevention Software.
Electronic platforms that support synchronous and asynchronous communication through a variety of software, services, devices and channels are called collaborative e-platforms.
Typical web-based collaborative e-platforms support synchronous and asynchronous communication, and therefore enable more effective team collaboration
Synchronous communication: real time multi-user communication, requires that all parties involved in the communication be present at the same time.
Examples: Data conferencing, Instant messaging, LAN messenger, Videoconferencing, Voice chat, VoIP, Web chat, Web conferencing
Asynchronous communication: does not require that all parties involved in the communication be present at the same time.
Examples: Blog, E-mail, Electronic mailing list, Message Board (Internet forum), Wiki
Synchronous: Defense Connect Online (DCO)
A wiki is a website that can be edited by anyone who is granted permission.
It is simple and powerful knowledge sharing and collaboration online tool that solves problems of Document management for a Team Project Management in an enterprise.
Other advantages of wiki:
cheap or free, simple enough for non-technical employees to use.
Detailed instructions on how to create a wiki page are available at http://www.umich.edu/~umctdocs/Wiki.html
Wiki at NNMC
GoogleDocs is a free web-based collaborative software. It has applications of word processors, spreadsheet and presentations that are similar to Word, Excel and PowerPoint.
Several useful functions are: autosave, revision history and rename of the files.
It allows users to create
and edit documents online
while collaborating in
real-time with other users.
Hulley, S. et al.(2007), Designing Clinical Research, 2nd ed. Lippincott Williams & Wilkins
On Being a Scientist: A Guide to Responsible Conduct in Research: Third Edition. (2009). Committee on Science, Engineering, and Public Policy,
National Academy of Sciences, National Academy of Engineering, and Institute of Medicine. http://www.nap.edu/catalog/12192.html
My Contact Information:
Marina Borovok, PhD
Head of Research Education
Clinical Investigation Department
Professional Education Directorate
National Naval Medical Center
8901 Wisconsin Avenue,
Bldg. 1, Rm. 4372,
Bethesda, MD 20889
E-mail: [email protected]