Organic photochemistry and pericyclic reactions (CY50003) 3-0-0. Course content.
Principles of photochemical reactions; Excited states and their properties; experimental set up for photochemical reactions(1); Several useful photochemical reactions and their applications in organic synthesis (isomerization, Patterno-Buchi reaction (1), Norrish type I and II reaction(1), Photoreduction, Rearrangements: di-π-methane, oxa di-π- and aza di-π-methane rearrangements(2), Photocycloaddition (2), Photochemical aromatic substitution reaction (1), Reactions with singlet oxygen (1), Photochemical methods for protection and deprotection(2). Photochemistry of biological systems (photosensitized reactions of DNA/RNA, DNA damage and repair-1).
Ground state (E0) and two excited states (E1, E2) of a molecule (vibrational and rotational levels are not shown).
Synthetic organic chemist (high intensity
light source, easy to handle, various
Flask size, specially designed systems)
Physical chemist or physical-organic
Chemist (mechanistic study)
# Immersion wells
# Reaction flasks
# Standard flasks
# Gas inlet flasks
# Flow-through flasks
# Larger capacity standard flasks
Non-Rotating AnnularPhotochemical Reactor
# Large Quartz immersion well.
# 400 watt medium pressure mercury lamp.
# Reactor base and carousel assembly
(non rotating), including support rod
and immersion well adjustable clamp.
# set of sample tube support rings for
eight 25mm sample tubes
# Only the inner or the outer tubes may be
irradiated effectively at one time
# UV Screen:- consisting of three black coated
consisting of three black coated aluminum
sections. A light tight lid, a removable front
and back section, that are joined by means
of a light tight seal
The semi-micro is a low cost, easy-to-use device for irradiating a standard
1 cm cuvette (or small tube) with either 254nm or 350nm radiation for any
preset time between 1 and 70 minutes. This reactor is ideal for preliminary
studies of small volumes of solution.
# The multilamp reactors consist of a base, lid, six or three lamp modules. Each module contains two lamps.# The base is hexagonal and provided with a centrally located fan# A number of modules up to six or three may be operated.# Switches are provided to control the fan and lamp modules.# Supports from the lid hold samples inside the reactors. Magnetic strips are used to eliminate light leaks between the lamp modules.
Multilamp Reactors: Six and Three Modules
Complete photochemical reactor comprising: three lamp modules. Each module contains two lamps.
Transmission characteristics of various solvents three lamp modules. Each module contains two lamps.
Measured for a 1cm path length of pure solvent
Norish Type I Processes of Ketones Basic Concepts three lamp modules. Each module contains two lamps.
JACS, 1977, 99, 3723-33 1,4-biradicals formed by
Mechanism I 1,4-biradicals formed by
Bioluminescence 1,4-biradicals formed by
Artistic rendering of bioluminescent Antarctic krill
Image of bioluminescent 1,4-biradicals formed by red tide event of 2005 at a beach in Carlsbad California showing brilliantly glowing crashing waves
containing billions of Lingulodinium polyedrumdinoflagellates
Photochemical reactions with singlet Oxygen 1,4-biradicals formed by