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B. A. rs6495446 in MTHFS. FHS. ARIC visit 1. ARIC visit 4. ARIC prospective. -5. -3. 0. 1.0. 1.5. 2.0. 2.5. 3.0. -1. 1. eGFR, ml/min/1.73m 2 per C allele. OR / HR of CKD per C allele. FHS. ARIC cross-sectional. ARIC prospective.

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FHS

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Fhs

B

A

rs6495446 in MTHFS

FHS

ARIC visit 1

ARIC visit 4

ARIC prospective

-5

-3

0

1.0

1.5

2.0

2.5

3.0

-1

1

eGFR, ml/min/1.73m2 per C allele

OR / HR of CKD per C allele

FHS

ARIC cross-sectional

ARIC prospective


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