CHAPTER 10 Infection and Immunity. Outline. 10.1 Infection 10.2 Non-specific immunity 10.3 Specific immunity 10.4 Medical Immunology. 10.1 Infection.
Girl infected with smallpox.
The last known person in the world to have smallpox of any kind. Variola minor in 23-year-old Ali Maow Maalin, Merka, Somalia CDC.
Child with polio sequelae.
Plasmodium10.1.2 Other microbial pathogenesis
Antiviral action of interferon
Lymphocyte agranulocyteDefense Cells in the Blood: The Leukocytes
Defense Cells in the Tissue: Macrophages, Dendritic Cells and Mast Cells
A Macrophage Phagocytosis of E. coli
A normal capillary prior to inflammation.
Integrins on the surface of the leukocyte bind to adhesion molecules
on the inner surface of the vascular endothelial cells.
The leukocytes flatten out and squeeze between the endothelial cells to
leave the blood vessels and enter the tissue.
The increased capillary permeability also allows plasma to enter the tissue.
External view of leukocytes squeezing between the endothelial cells,
leaving the blood vessels, and entering the tissue.
Central immune organ: Thymus
Human T-lymphocyte attacking fibroblast tumor cells.
B cells mature into plasma cells that produce antibodies.