A. HRICHI, S. KOUKI, M. LANDOULSI ,R. AOUINI, I. GANZOUI, S.BOUGUERRA, Y. AROUS, H. BOUJEMAA, N. BEN ABDALLAH Radiology service, Main Military hospital of Instruction of Tunis, Tunisia. A RARE CASE OF MULTIPLE CYSTIC METASTASES IN THE BRAIN FROM ADENOCARCINOMA OF THE LUNG . CH7. Inroduction :.
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A. HRICHI, S. KOUKI, M. LANDOULSI ,R. AOUINI, I. GANZOUI, S.BOUGUERRA, Y. AROUS, H. BOUJEMAA, N. BEN ABDALLAH
Radiology service, Main Military hospital of Instruction of Tunis, Tunisia
A RARE CASE OF MULTIPLE CYSTIC METASTASES IN THE BRAIN FROM ADENOCARCINOMA OF THE LUNG
Severaldiseasescan present with multi-cystic brain lesions:
1- Positive diagnosis
2- Approach of etiologicdiagnosis:
the main question!
A rare case of cystic intracerebral metastases from adenocarcinoma of the lung
CT brain Scan was indicated
CT brain scan without(a) and with(b) injection of iodinated contrast: multifocal hypodense lesions(a) with partial peripheral contrast enhancement(b) but without significant perifocaloedema.
Further brain MRI was performed and allowed to objectify:
multifocal cystic lesions with partial peripheral contrast enhancement but without significant perifocaloedema.
a1 a2 a3
b1 b2 b3
Axial T1-weighted with (a1, a2, a3) and without gadolinium (b1, b2, b3):nodularhypointense multiple extra-axial lesions, with partial peripheral contrast enhancement.
a1 a2 a3
b1 b2 b3
Axial T2-weighted (a1, a2, a3) and FLAIR (b1, b2, b3): Multiple hyper-T2 hypo-FLAIR extra-axial lesions (cysticlesions).
a1 a2 a3
b1 b2 b3
axial diffusion (a1, a2, a3) and ADC (b1, b2, b3):
Multiples nodularlesionshyperintense in diffusion with a low ADC.
→ usually: as well-circumscribed densely enhancing masses with surrounding vasogenic edema.
→ can be misdiagnosed as: brain abscesses, primary cerebral tumors, or parasitic infections, especially in patients without a history of malignancy.
Cystic cerebral metastases have been described in carcinomas of :
However, and in reviewing the literature:
-We have only found 2 similar cases reports of lung adenocarcinoma with cystic cerebral metastases.
-In both of them, the patients were already followed for bronchial adenocarcinoma.
- while in our case, cystic cerebral metastases revealed the disease.
This case demonstrates an unusual pattern of cerebral metastases of a bronchial adenocarcinoma. This constellation should be considered in the differential diagnosis of cerebral cystic lesions even in patients without a history of malignancy, and wich is necessary to evoke at every smoking adult's of about forty. The exact nature of which might be difficult to assess without biopsy.
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