Optical Topography: An overview. Nima Kasraie Spring 2007. What When Where. Oxymetric Near Infrared Imaging Images higher order brain functions Developed by Hitachi Advanced Research Laboratory Already in clinical use in Japan. Red Light Transmission . Features. Small Easy to use
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3cm ≈ dcortex
Similarities with fMRI (Hb, HbO) and metabolic responses to visual stimuli with unknown origin have been observed.
fMRI measures differences between the Fe content in blood based on the metal’s response to the magnetic field.
OT relies on different light absorption characteristics of the two forms.
Lower spatial resolution than fMRI
2mm vs. 20mm
Higher temporal resolution than fMRI
1 Sec vs. 1 mSec
OT does not measure exact blood volume concentrations; it measures concentration changes of molecular species, including oxyhemoglobin and deoxyhemoglobin.
References and further reading (Hb, HbO) and metabolic responses to visual stimuli with unknown origin have been observed.