生命的省思. 周成功 陽明大學生命科學系 [email protected] 生命是什麼？. 地球生命的起源 ?. 來自外太空 ? 發生於地球 ? 無論發生地何在，問題仍舊一樣 「生命如何開始？」 「細胞的資訊系統如何形成？」. Stanley Miller and origin of life. Harold Urey 1950. The building blocks of life can be formed from inanimate environment ！. What is life? E. Schrondinger, 1943.
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The building blocks of life can be formed from inanimate environment！
Using physical barrier to isolate internal structure from external aqueous environment
Metabolic reaction network in one single cell to extract energy from the food .
Genetic program ( a set of genes or genome ) instructs the formation of such network ( hardware ) from generation to generation!
May 21, 1953 at Cambridge
-.-. .- -
11000011 01000001 11010100
43 41 54
C A T
C A T
- 30,000 – 40,000 genes
- 3,000,000,000 genetic codes
- 23 chromosome
- In almost every single human cells except red blood cells
“Any living cell carries with it the experiences of a billion years of experimentation by its ancestors”
From “ A physicist looks at biology” by Max Delbruck, 1949
Is biology an autonomous science?
Whether and how biology differs from the physics?
How the physicist views biology?
“Postage stamp collection”
By Ernest Rutherford
“A mature physicist, acquainting himself for the first time with biology, is puzzled by the circumstance that there are no ‘absolute phenomenon’ in biology. Everything is time-bound and space-bound. The animal or plant or micro-organism he is working with is but a link in an evolutionary chain of changing forms, none of which has any permanent validity.”
By Max Delbruck
What is the cause of bird migration to south in the autumn?
Biology: a science with evolutionary history
Future challenge in life science
“The genetic program is the product of a history that goes back to the origin of life, and thus it incorporates the “experiences” of all ancestors.”
From “Is biology an autonomous science?”
By Ernst Mayr 1985
"Nothing in biology makes sense except in the light of evolution."
T. Dobzhansky 1900 - 1975.