1 / 11

Chemical Sensor - Cation Detection -

Chemical Sensor - Cation Detection -. 2002. 10. 02. Young Sik Lee Information & Communication Materials Lab. Introduction. History. Application of Cationic Sensor. 1860 Copper wire as a thermoelement 1923 Catalystic combustion-type sensor 1952 Galvanic cell-type gas sensor

eytan
Download Presentation

Chemical Sensor - Cation Detection -

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Chemical Sensor - Cation Detection - 2002. 10. 02 Young Sik Lee Information & Communication Materials Lab.

  2. Introduction History Application of Cationic Sensor 1860 Copper wire as a thermoelement 1923 Catalystic combustion-type sensor 1952 Galvanic cell-type gas sensor 1962 Basic concept for biosensor 1967 Discovery of cation-complexing macrocyclic polyethers (crowm ether) 1968 Fluorosensor for oxygen determination 1972 Ca2+-selective electrode based on a tailored synthetic neutral carrier 1974 First synthetic neutral carrier with enantiomer-selective behavior 1977 Emzyme PET 1980 Fiber optic Ph probe for physiological use 1985 Evaluation of the first optical potassium sinsor based on valinomycin and dry-reagent marcketed by Ames 1990 Demonstration of a working biotest based on catalystic antibodies 생체내에서 금속이온들은 중요한 역할을 하게된다. 이중에서도 Na+, K+, Cl-, Mg2+, Mn2+, Ca2+, Fe2+, Zn2+, Cu2+ 등을 예로들면 1가 이온들은 시경자극의 전달과 혈액의 전해질 균형 유지에 필요하다. 2가 이온과 3가 이온은 가끔 효소와 결합하며, 효수활성에 필요하다. 이들은 모두 미량으로 존재하기 때문에 미량분석을 할 수 있는 방법의 일환으로 연구되어지고 있다. 그리고 환경적인 측면에서도 금속이온을 검출해내는 일은 중요하다.

  3. Problem : Unpredictable Signal Suggestion : Introduction of Two fuctional Signal Units Sensory Materials Felix Sancenon, Teresa Pardo, Juan Soto. Eur. J. Inorg. Chem. 2002, 866.

  4. Problem : Difficult to Detect Li+ Selectively from Na+ Suggestion : Steric Effect Sensory Materials Thorfinnur Gunnlaugsson, Bastien Bichell and Claire Nolan, Tetrahedron Letters, 42, 4989, 2002

  5. Problems : 1. Difficulty to Detect K+ Selectively from the Large Exess of Na+ 2. Low Selectivity for Cs+ Suggestion : Formation of Sandwich Complex with Particular Alkali Metal Ions Sensory Materials n=1, 2, 3 Wen-Sheng Xia, Russell H. Schmehl, Chao-Jun Li, Joel T. Mague, Chu-Ping Luo and Dirk M. Guldi, J. Phys. Chem.B, 106, 833, 2002

  6. Problems : 1. Poor Selectivity of Pure Polyaminic Ligands 2. pH Dependence 3. Water Soluble Suggestion : Introduction to Amio-amido Type Ligands and Hydroxyl Groups Sensory Materials Marta Beltramello, Maddalena Gatos, Fabrizio Mancin, Paolo Tecilla and Umberto Tonellato, Tetrahedron Letters, 42, 9143, 2001.

  7. Purpose : Improvement of Selectivity Suggestion : Designing Macrocyclic Analogue Depending on Metal Ion Size Sensory Materials Paul N. W. Baxter, J. Org. Chem, 66, 4170, 2001

  8. Purpose : Determination of very Low Contration of Earth Alkali Metal Ions and Zn+ Suggestion : Introduction to Pyrene Luminophore Sensory Materials Luca Prodi, Roberto Ballardini, Maria Teresa Gandolfi, Roberta Roversi, Journal of Photochemistry and Photobiology A: Chemistry, 136, 49, 2000.

  9. Contents : 1. Effect of Rigidity on Sensitivity and Selectivity Sensory Materials C-C Sing Bond Provides the Weakest Resistance to the Coplanarity Higher Response Sensitivity Macromolecules. 2001, 34, 7932. Bin Liu, Wei Huang

  10. Purpose : 1. Effect of Length of Spacer on Ion Sensing Ability Sensory Materials Anal. Chem. 2000, 72, 5841. Akiyo Ymauchi, Norio Teramae

  11. Problem : Increase Sensitivity of Small Molecular Chemical Sensor(SMCS) Suggestion : Cooperative Recognition Advantages of SMCS : Good Modification and Cell Permeability Sensory Materials R= J. Am. Chem. Soc. 2000, 122, 4522. Timothy E. Glass.

More Related