Just enough biochemistry to be dangerous??. http://www.detoxi-pad.com/. Just enough biochemistry to be dangerous??. http://www.tahitiannoni.com/united_states/english/retail/store/research/index.html. Chapter 15. Design of metabolism. http://www.chem.uwec.edu/Chem454_S08/MetabolicchartBig.pdf.
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Design of metabolism
BUT,it’s kinetically stable
"High energy" substance: a thermodynamically unstable substance whose hydrolysis or decomposition can be easily coupled to an unfavorable reaction. The arbitrary cut-off is~-10kJ/mol. There is no such thing as a "high energy bond" per se.
Free energies are additive; favorable rxns can drive unfavorable;e.g.sequential coupling
Example:Glucose to glucose-6-phosphate
Metabolic strategies-Oxidation(burning of carbon containing compounds)
e.g. Substrate Cycling:
See glycolysis (F-6-P to F1,6-BP)