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Load regulates bone formation and s clerostin expression through a TGF  -dependent mechanism

Load regulates bone formation and s clerostin expression through a TGF  -dependent mechanism. Osteoscoop - Issue N°297 – July 2013. Osteoblast. Osteoclast. Mechanical load. >. Bone resorption. Bone formation. Osteoblast. Osteoclast. Mechanical load. <. Bone resorption.

erin-osborn
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Load regulates bone formation and s clerostin expression through a TGF  -dependent mechanism

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  1. Load regulates bone formation and sclerostin expression through a TGF-dependent mechanism Osteoscoop - Issue N°297 – July 2013

  2. Osteoblast Osteoclast Mechanical load > Bone resorption Bone formation

  3. Osteoblast Osteoclast Mechanical load < Bone resorption Bone formation Scl Scl Scl Scl Scl Smad3 - P SOST TGFb TbRI/II Osteocyte

  4. Osteoblast Osteoclast Mechanical load > Bone resorption Bone formation Scl Smad3 - P SOST TGFb TbRI/II Osteocyte

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