gene mutations
Download
Skip this Video
Download Presentation
GENE MUTATIONS

Loading in 2 Seconds...

play fullscreen
1 / 14

GENE MUTATIONS - PowerPoint PPT Presentation


  • 77 Views
  • Uploaded on

GENE MUTATIONS. 2011. MUTATION Change in the genetic material (DNA). CAUSES OF MUTATIONS 1. Errors during DNA replication 2. Radiation and toxic chemicals 3. Viruses 4. Errors during formation of egg and sperm cells. IMPACT OF MUTATIONS DEPENDS ON THE CELL IN WHICH THEY OCCUR

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about ' GENE MUTATIONS' - erich-french


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
slide2
MUTATION

Change in the genetic material (DNA)

slide3
CAUSES OF MUTATIONS

1. Errors during DNA replication

2. Radiation and toxic chemicals

3. Viruses

4. Errors during formation of egg and sperm cells

slide4
IMPACT OF MUTATIONS DEPENDS ON THE CELL IN WHICH THEY OCCUR

1. Somatic Cell: may lead to cancer

2. Gamete Cell (sperm or egg)

  • Sterility (organism can’t reproduce)
  • Passed to offspring (birth defect)
slide5
GENE MUTATIONS

Alters the DNA sequence of one gene on a chromosome

  • Affects the body’s ability to synthesize one type of protein.
  • All copies of that protein in the body may be defective.
slide6
TYPES OF GENE MUTATIONS
  • Point mutation
  • Frameshift mutation
slide7
POINT MUTATION

Changes one base pair in the DNA sequence of a gene

Ex: CAT TAG CAT GAG

slide8
OUTCOME OF POINT MUTATIONS

1. One amino acid is altered and the protein is defective.

slide9
Normal Mutated

DNA AAA CCG ATT AAA TCG ATT

mRNA UUU GGC UAA UUU AGC UAA

A.A PHE GLY STOP PHE SER STOP

slide10
Alteration codes for the same amino acid and the protein is normal.

(a benefit of the genetic code’s redundancy)

slide11
Normal Mutated

DNA AAA CCG ATT AAA CCA ATT

mRNA UUU GGC UAA UUU GGU UAA

A.A PHE GLY STOP PHE GLY STOP

slide12
FRAMESHIFT MUTATION

One or more base pairs are added or deleted from the DNA sequence of a gene

Ex: CAT TAG CTT AG

slide13
IMPACT OF FRAMESHIFT MUTATIONS

If the addition or deletion is NOT a multiple of three, all amino acids after the mutation are altered and the protein is defective.

slide14
Normal Mutated

DNA AAA TGG CCG ATT AAA GGC CGA TT

mRNA UUU ACC GGC UAA UUU CCG GCU AA

A.A PHE THR GLY STOP PHE PRO ALA

ad