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T: OS TS S T

?????S??????s??p?????ta? ??a: t?? ?p?st????? ?a? sta?e??p???s? ?a???, ?a??????, ??p?es??, t?? ?p?st????? ????? ? ?????s??, t?? pe?????s? t?? ????t???t?ta? (a????t?p???s?), t?? pe?????s? ??d?at??, t? e??s? t?? p????.. ??????????? ?????S??????s??p?????ta? ??a ste???s? ep??e?t??, ??e

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T: OS TS S T

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    1. ??T???: ??O??S ???T???S ?????S??? ??? ???T????? ?. ?IEKKAS

    2. ?????S??? ???s?”?p?????ta? ??a: t?? ?p?st????? ?a? sta?e??p???s? ?a???, ?a??????, ??”p?es??, t?? ?p?st????? ”????? ? ?????s??, t?? pe?????s”? t?? ????t???t?ta? (a????t?p???s?), t?? pe?????s”? ??d?”at??, t? ”e??s? t?? p????.

    3. ??????????? ?????S??? ???s?”?p?????ta? ??a ste???s? ep??e”?t??, ??e??? a?”???a??a?, pe?????s”? ????t???t?ta?, ?p?st????? d?ast?e””?t??. ??p??: - d??t??t??: a?a?? p???? (ae??s”?? p?????), a?at??????? ??a t?? ?s??s? p?es?? ? t?? ?p?st????? a????se??, - ep?des”?? ”e e????? p??sa?”??? st? s??”a t?? ”?????: ste???s?, ?p?st?????, - ep?des”?? ap? e?ast??? ?????: ?p?st????? se a????se?? (ep????at?de?, pe??sf???de?).

    4. ??????S ?F????G?S ??????????? ?????S??? (1) Sta?e?te ”p??st? ap? t? t?a?”a. ??ate?ste t? ???? st? ??s? p?? ?a pa?a”e??e? ”et? t?? ep?des?. ??ate?ste t?? ep?des”? ?ts? ?ste ? ep?f??e?a p?? ?a a???”p? st? t?a?”a ?a ”?? ??e? ???e? se epaf? ”e t? ???? sa? (a?t? p?? t?? ??at?e?). ? ep?des? ?e???? t?p??et??ta? t?? ???? t?? ep?des”?? st? t?a?”a.

    5. ??????S ?F????G?S ??????????? ?????S??? (2) G????ta? d?? a?????? pe??st??f?? ??a ?a ste?e??e? ? ep?des”?? ?a? st? s????e?a t????eta? spe???e?d??, ap? t?? es?te???? p??? t?? e??te???? p?e???. ?et? t?? t?p???t?s?, ???e 10 ?ept?, e????eta? ? ?????f???a t?? a?”at??, ?d?a?te?a a? ???s?”?p?????ta? ep?des”?? p?? p??sa?”????ta? st? s??”a t?? ”????? (p?????s? ??d?”at??).

    6. ???O???? ?????F???? ??????S ?? d??”a t?? ????? ???eta? ???? ?a? ?????te?? ap? t? ?p????p? d??”a. ? as?e??? d?a”a?t??eta? ??a ”??d?as”a ?a? ad??a”?a ????s??. ???????O??S? ?et????te t?? ep?des”? ”???? ?a epa????e? t? ???”a ?a? ? ?e?”???as?a t?? d??”at??. ????ete ”e t? ???? st?? p??ß??”at??? pe????? ”???? ?a asp??se?. ?ta? t? af?sete, t? ???”a p??pe? ?a epa????e? a”?s??. ?a?at????te t?? ep?des”?.

    7. ??G?T? ??????????? ?????S??? ? ep????? e?a?t?ta? ap? t? ”???? st? ?p??? ?a ???s?”?p????e? ?a? p??pe? ?a e??a? p??? p?at?te??? ap? t? t?a?”a: 2,5 cm ??a t? d??t???, 5 cm ??a t?? ???a ?e??a, 7,5-10 cm ??a t? ß?a????a, 10-15 cm ??a t? p?d?

    8. ?????? ?????S?S ??????????? ?????S???

    9. ?????S? ?G?O?? – G?????S ??? ????? ?????? – ?????? - Sta?e??p???s? ep??e”?t?? ? ?p?st????? t?a?”?t?? ”a?a??? ”????? (d?ast??””ata) ? ?ata?”?t??. - ?pa?te?ta? fa?d?? ep?des?: ? t?p???t?s? t?? ep?d?s”?? ?a e?te??eta? p??a ap? t?? ?????s?. - S??p??: ? ?s??s? epa????? p?es?? st?? t?a?”at?s”??? pe?????.

    10. S?????? se ?at??”ata ß?a??????? ?a? ?e???da?. ???d???? t??s?? a??e???-?e????: apa?a?t?t?? ? ??e???? t?? ?????f???a?.

    14. ???”esa sta d?? p?d?a t?p??ete?ta? apa?a?t?ta ”?a pets?ta d?p??”??? se ?????d???? s??”a (p????? a????t?p???s?). ? ??”p?? ?at? p??t?”?s? t?p??ete?ta? st? e?d??”es? ?e?? t?? p?d???. ??a??a?t???, efa?”??? ?f?s”at?? p???? t?? p????? (sa? a???a).

    15. S????? st??? ??????”?????. ??s?”? p?s???t?? ????? ”e t? ????? (a????t?p???s?). ??? st??f? ???at??-p?d???: e??????””?s? p?d??? ”e ???? ?at? t?? ep?”??? ????a. ?p?des? st? ???? ”????, ????t??, ast?a?????.

    16. ??s?”? p?s???t?? ????? ”e t? ????? (a????t?p???s?). ???????””?s? p?d??? ”e ???? ?at? t?? ep?”??? ????a. ?p?des? st? ???? ????t??, ast?a?????.

    17. ???GO????? ?????S??? ?p?????? ?t??”?? se ap?ste???”??e? s?s?e?as?e? ? ?atas?e?????ta? d?p?????ta? ? ??ß??ta? ??a tet?????? a??e?t??? ?fas”a d?a????a. ???s?”?p?????ta? ??a ste???s? ep??e”?t?? ? ??????a, ?? a?a?t??e? ? p?ate?? ep?des”??, ??a t?? a????t?p???s? ”e??? ?a? t?? ?p?st????? d?ast?e””?t??.

    18. F????S ??? S????S ???GO????S ?????S??S

    19. S???????????

    20. ?????S? ????? ?????? - ??????

    21. ?????S? ????O??? ??F???S

    22. ?????S? ??????S

    23. ?????S? O???

    24. ?????S? TO???? - ????S

    25. ?????S? G?????? - ?S????

    26. ????????S ?????S??? ???s?”?p?????ta?: ??a ?a ?p?st??????? t?a?”at?s”??? ß?a????a ? ?a?p?, ??a ?a ”e??s??? t? ß???? t?? ß?a????a ap? e?a????”??? ?”?, ??a ?a a????t?p???s??? t? ß?a????a ep? ????s?? t?? d??????s?? t?? ?”??, se t?a?”ata st? ????, ??a t?? ??e??? t?? a?”???a??a? ?a? t?? pe?????s”? t?? ??d?”at??. ? as?e??? p??pe? ?a e??a? se ?a??st? ??s? ?a? ?a ?p?st????e?, a? ”p??e?, t?? t?a?”at?s”??? ß?a????a.

    27. ?F????G? ???????? ?????S??? (1)

    28. ?F????G? ???????? ?????S??? (2)

    29. ????S?????? ????????S ?????S???

    30. S??????S??S ?????????????S ?????S???

    31. ????T???S? ?????????????S ?????S??? S? ??????? ????G??

    32. ????S???? ????S?????? ???????? ??????

    33. ???OS??S S?????????S S????S

    34. ?F????G? G????O? ?????S?O? ?fa?”??eta? se e?d??”es? st??”a ß?”ßa??? (p??stas?a d??”at??), ? ????ta???a t?p??ete?ta? ?p? t?s?, ?p???e????ta? t??? ?st??? se e?af?? ?p?????s?, S?”pe???a”ß????ta? ?? e?at????e? t?? ?at??”at?? a????se?? (e?t?? ?e???da?-???”??), ?? ?p??e? a????t?p?????ta? se ?e?t??????? ??s?, ?a ?e??a p??state???ta? ”e p??s?et? st??”a ß?”ßa???, ?fa??es?: ap?f??? t?a?”at?s”?? t?? d??”at??. ?? ????p????? (e?te?e? pa?”??? ????s?) de? p??pe? ?a s??eta? ?at? ”???? t?? ????? (pa???s?a ?a???).

    35. ?????????T?S? ?ST??O? ?? G????? ?????S?? ??????p? ??s? ??t? ????? ? a???t?s? ??? ????? ap? t?? a????a (?p?ß????s? f?eß???? epa?af????), ??e?e???s? ?a? a?t?”et?p?s? p????, ??e???? ?????f???a? t?? ”?????: ? ?????s? ????? ?p?d????e? f?eß??? ????”a, e?? ta ?e??? ?a? ????? ???a a?t???a?? ß??ß?, a?s??t???t?ta d??”at??, ???t??a: e??tas? ??a ??d?”a, e???????s? t?? as?e?? ?a e?te?e? ????se?? (f?eß??? ep?st??f?), ??e???? pa??t???? ????s?? (p????: ?s?a?”?a t?? ?a”pt???? ”???), ??e???? e?e???se?? d??”at?? (p?es? st?? es?te???? ep?f??e?a t?? ?????): t?p???? p????, d?s?s”?a, e????, p??et??, ???a?? ? afa??es? ?????.

    36. ???T????? ???s?”?p?????ta? ??a: t?? ??e??? t?? a?”???a??a? (a?”?stas?), t? ”e??s? t?? ???d???? ep?”????s?? t?? p?????, t?? p??a???? t?? ep????s?? (p??stas?a ?e?s??”at???”e??? ep?????a??? ?st??), t?? e?asf???s? ? t?? ap?”?????s? (ap????f?s?) t?? ???as?a?, t? ”e??s? t?? p????.

    37. ??????S ?F????G?S ???T????O? (1) ???s?”?p???ste ap?ste???”??a ???t?a ??a t?? p?????? ”et?d?s?? ???”??e??. ?a?a??ste p??se?t??? t? t?a?”a: ap?”a????ete ???a s?”ata ? ?e????? ?st???. ??p??et?ste a?t?ß??t??? a???f? st?? es?te???? ep?f??e?a t?? ep???”at??. ?? ep??e”a p??pe? ?a epe?te??eta? p??a ap? ta ???a t?? p????? (p????? ??????) ?a? ?a ”?? ??e? ???e? se epaf? ”e ???e? pe??????. ?? d?ap?t?ste? ap? a?”a, t?p??ete?ste de?te?? ep??e”a p??? st? p??t?.

    38. ??????S ?F????G?S ???T????O? (2) ??? a????ete ”e ta ????a t?? p???? ? t?? es?te???? ep?f??e?a t?? ep???”at??, ap?f??ete ?a ß??ete, ?a fta???ste?te ? ?a ”???sete p??? ap? t?? p????. Ste?e?ste ”e t?? efa?”??? ep?d?s”?? ? ad??ß????? p?ast???? a? ? pe????? a?a”??eta? ?a e?te?e? se ?e??. ?a ????? p?? ???s?”?p??????a? t?p??et???ta? se p?ast??? sa????a p?? ?atast??feta? se ???ßa??. ??t?ste t?? as?e?? ??a pa???s?a p????, sf???”at??, a? a?s???eta? t?? pe????? ?a? a? ”p??e? ?a ????se? t? ”????.

    39. ??????S ????G?S ???T????O? (1) ?????ste t? d?ad??as?a st?? as?e??. S???e?t??ste ta ?????. ? a??a?? de? apa?te? s?????? d?ad??as?e? ap?ste???s??. ?f?? f???sete ap?ste???”??a ???t?a, afa???ste t? ep??e”a. ?? ??e? ?????se?, ? ????s? f?s????????? ???? t? ß???? ?a ?a?a??se?. ???????e?ste t?? p???? ??a s?”e?a ???”???? (e????, d?s?s”?a) ?a??? ?a? ??a t?? p???d? t?? ep????s??. ??ßete ?p??? t? d?sf???a t?? as?e?? ?at? t? d?ad??as?a.

    40. ??????S ????G?S ???T????O? (2) ?a?a??ste t? t?a?”a ”e f?s???????? ???. ?????te ap?ste???”??a ???t?a. ??p??et?ste t? ??? ep??e”a ?a? ste?e?ste t? ?at?????a. ?a ????? p?? ???s?”?p??????a? t?p??et???ta? se p?ast??? sa????a p?? ?atast??feta? se ???ßa??. ?ata????te ?at?????a t? d?ad??as?a ?a? p??a??? pa?at???se??.

    41. ????? ???T????O? (1) G??e?: ap?ste???”??e? ?fas”?t??e? d?”?? ap????f?t???? ß?”ßa??? ? s???et???? ??????, ???s?”?p?????ta? ?d?a?te?a st? ?e????????? (ßa??? t?a?”ata). ??t??????ta: ???a ? ??tta???? p??? se a?t??????t? ?????, ???s?”a ??a ”????? p????? (e?d??? ??a a????e?, ft???e?, d??t??a). ?d???????e?d?, ?d?????d?: a?t??????ta, ??a e??ss??a e??a?”ata, ???? ?ata???se?? ?a? t?a?”at???? ?a??se??, s??”at????? gel ?a??? ap????f??? ???? ap? t? t?a?”a. Hydrogels: ?????? ??a ”???s”??a t?a?”ata ? ”e ?e????? ?st???, ??? se t?a?”ata ”e pe?????s”??? ?????s? ????? (af?d?t?s?).

    42. ????? ???T????O? (2) ?d??p???”e??: d?a??t??? p???ap?? st??”ata, ap????f??? ???? ?a? d?ast?????ta? ?ste ?a ?a?????? t? t?a?”a. ?pe?ap????f?t???: ?????? ????t???t?ta?, ta?e?a ap????f?s?. ???????e?????: d?a??t??? ”??????, a????t??? ?a??”??? p?? ap????f??? ????. ???s???et???, ????a?????: ?atas?e?????ta? ap? ??????? ?st??? ?a? p???”e??. ???s?”?p?????ta? se e??a?”ata ?a? d?s???a st?? ep????s? t?a?”ata a?t?st???a.

    43. ????? ???T????O? (3) ??afa?e?? ”e”ß???e?: de? ??????? se ????? ep?f??e?e? ?a? ap?t??p??? t?? e?s?d? ßa?t????? ?a? ????? st? t?a?”a (ep? ?????? ???d???? ???”????). ?e pa?????te? a??pt????: ep?d???? se s???e???”??a ??tta?a ep?ta?????ta? t?? ep????s? (d?aß?t??? p?d?). ?p??at?stata d??”at??: p???????ta? ap? a????p??a ??tta?a p?? ?a???e?????ta? ?a? d?ast?????ta? in vitro (?????? ??a f?eß??? ???? p?d???).

    44. ??????????? ???T???

    45. G???

    46. HYDROGEL

    47. ????????S??S ?a ep???”ata p??pe? ?a ???s?”?p?????ta? ”e p??s??? st?? pe??pt?s? pa???s?a? Gram (-) ßa?t????? (af?????? se pe??ß?????ta ?????? ???as?a?) ?a? se as?e?e?? ”e a??s??atast???. S?”a?t??? ? s???? a??a?? t?? ep??e”?t??. Hydrogel: e?????? t?? a??pt??? Gram (-) ßa?t????? st?? pe??pt?s? p?? a?t? e?s?????? st? t?a?”a. Hydrogel ?a? ?d???????e?d?: ?da???? ??a ßa??? t?a?”ata: ap????f??? ta ???? p?? e???????ta?, e?asfa?????? ???as?a apa?a?t?t? ??a t?? ep????s?, p??sf????? ??es? st?? as?e??. ???????e?????: ?da???? ??a t?a?”ata p??s?p??: ße?t??”??? a?s??t??? ap?t??es”a (pe?????s”?? ????d??? ?st??).

    48. ??????S ?F????G?S ???T????O? S? ?G????????S ??a?”at?p??e?ta? ”et? t? ??????s? a?a???s?a?. F???ste ep?p???? ????””a ”a????? ?a? ?e????????? ”?s?a. ? s?””et??? t?? as?e?? st? d?ad??as?a t?? pa???e? ??p??? ßa?”? e?????? st?? p???. ???a?? ?a ??e?ast??? ?a??d?a ?a? ?aß?de? ??a t?? afa??es? t?? ep??e”?t?? ?a? t?? ?e???t???? es???a?. ???????e?ste t?? e??a?”at???? pe??????, ?a?a??ste ?at?????a ?a? t?p??et?ste t?? apa?a?t?te? a???f??. ?? ???a?”a ?a??pteta? s?????? ”e p???ap?? st??”ata ep??e”?t??. ? t?p???t?s? t?? ep???”at?? p??pe? ?a ep?t??pe? t?? ????s? t?? ????? (e?t?? a? a?t? a?te?de????ta?).

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