Use preformed components to non-specifically clear the agent

Use preformed components to non-specifically clear the agent PowerPoint PPT Presentation


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Use preformed components to non-specifically clear the agent

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6. Cells and Tissues of the Immune System Lecture 2

7. Cells of the Immune System Tissues/Organs of the Immune System

8. Cells of the Immune System

9. Hematopoiesis

10. Lymphocytes

12. B Cells T Cells NK Cells

18. Mononuclear Phagocytes Monocytes and Macrophages Dendritic Cells

19. Functions Phagocytosis Antigen processing and presentation (APCs) Activation of T cells

20. Origin and Development of Macrophages

22. Dendritic Cells Transport Antigens to L. nodes Initiation of T Cell Responses

23. Dendritic Cell Subsets

26. Lymphoid Organs

27. Lymphoid Organs

28. Lymphoid Organs Primary (Generative) Lymphoid Organs maturation site of lymphoid cells bone marrow, bursa of Fabricius, thymus, Peyer’s Patches in Pigs and Ruminants Secondary Lymphoid Organs efficient at trapping and concentrating foreign substances site of Ag-driven proliferation and differentiation; e.g. Ab production spleen, lymph nodes, diffuse tissues

29. Primary Lymphoid Organs

30. Thymus Site of T cell maturation. Relative Size Greatest in Newborn Absolute Size Greatest at Puberty

33. Effect of Thymectomy in Adult

34. Bone Marrow Site of hematopoiesis. Site of B cell maturation in mammals.

35. Bursa of Fabricius Site of B cell maturation in birds.

36. Peyer’s Patches Site of B Cell Maturation -Pigs and Ruminants

37. Secondary Lymphoid Organs

39. Lymph Nodes Local sites of specific immune response. Strategically placed on lymphatic channels.

43. Spleen Site of immunological responses against blood-borne Ags. White pulp rich in lymphoid cells. Red pulp rich in Macrophages.

48. Circulation of Naïve and Activated/Memory T Lymphocytes

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