Hemodynamic Disorders. Fluid Homeostasis. Homeostasis is maintained by the opposing effects of: Vascular Hydrostatic Pressure and Plasma Colloid Osmotic Pressure. ASCITES . Edema. Pitting Edema. PERIORBITAL (RENAL). Pulmonary Edema.
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Homeostasis is maintained by the opposing effects of:
sometimes blood-tinged fluid
with pulmonary function
the alveolar capillaries are engorged, and an intra-alveolar granular pink precipitate is seen
The surface of the brain with cerebral edema demonstrates widened gyri with a flattened surface. The sulci are narrowed
Clinical CorrelationThe big problem is: There is no place for the fluid to go!
LPS = lipopolysaccharide
TNF = tumor necrosis factor
IL = interleukin
NO = nitric oxide
PAF = platelet-activating factor
ARDS/diffuse alveolar damage in shock
Some of the alveoli are collapsed; others are distended. Many contain dense proteinaceous debris, desquamated cells, and hyaline membranes
MYOCARDIAL NECROSIS in Shock
lower field contains intact myocardium, while the upper field exhibits coagulation necrosis of myocardium. the hypoperfusion is greatest in the subendeocardium, which is perfused mainly in diastole.
ATN in shock , extensive tubular isghaemia , note relative sparing of the glomeruli.