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Current Topics in Medical Physics Research. Xiaoming Zheng, PhD. School of Dentistry and Health Science Chengdu, China, 2009. Current Research Interests . Image reconstruction algorithms Scatter and resolution corrections Image quality assessment Clinical image analysis

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current topics in medical physics research

Current Topics in Medical Physics Research

Xiaoming Zheng, PhD.

School of Dentistry and Health Science

Chengdu, China, 2009

current research interests
Current Research Interests
  • Image reconstruction algorithms
  • Scatter and resolution corrections
  • Image quality assessment
  • Clinical image analysis
  • Computer aided diagnosis
  • Radiation detectors
images reconstructions
Images Reconstructions
  • Iterative Reconstruction: Rescaled Block Iterative Algorithm including attenuation, scatter, and distance resolution compensation. Parameters tested: iteration 1,3,5,7,10 and post Gaussian filter FWHM 0,1,2,3,4 pixels
  • Filtered Back-Projection: Parameters tested: Butterworth filter cut-off frequencies: 0.10, 0.15, 0.20, 0.25 and 0.30 pixel-1
human and numerical observer image quality studies
Human and Numerical Observer Image Quality Studies
  • Human observer study using receiver operating characteristics
  • Numerical observer employing an ideal observer model.
slide20

Before Correction

After Correction

radiation dose optimization in ct
Radiation Dose Optimization in CT
  • Biological effect of ionizing radiation
  • Cancer rate vs radiation dose
  • Radiation dose reduction: image quality vs radiation dose
  • Technical parameters: kVp, mAs, etc.
computer assisted diagnosis
Computer Assisted Diagnosis
  • Provide second opinion to radiologists.
  • FDA approved systems include breast and lung cancer detections.
  • Image processing
  • Image data base
  • Artificial intelligence.
radiation detectors
Radiation Detectors
  • Room temperature Semiconductor Detectors: Materials and mechanisms
  • Magnetic resonance coils designs.
scintillator based gamma camera
Scintillator-based gamma camera

Detector head

(GE Medical Systems)

czt nai comparison
CZT / NaI comparison

ELGEMS CZT pixilated

small field imager

Anger camera (NaI)

Test image

Thyroid phantom

semiconductor czt
Semiconductor - CZT

g

CdZnTe: Gamma rays create electron/hole pairs. The gamma energy level is proportional to the electrical current.

X

CdZnTe (CZT)

E

h

+

e

-

new imaging systems
New Imaging Systems
  • New detector technology.
  • Optical imaging: visible, ultraviolet, inferred.
  • Molecular imaging: PET, fMRI, Optical
  • Hybrid imaging systems.
  • T Herts imaging.
slide42

Thickness of tissue probed

30 mm 100mm 1mm 1cm 10cm

l

400 nm

800 nm

1600 nm

10 mm

100 mm

Confocal/ multi-photon microscopy

Diffuse optical tomography

Optical coherence tomography

Thermography

THz imaging

medical physics topics
Medical Physics Topics?
  • Treatment of depression: Transcranial magnetic stimulation.
  • Killing of cancer cells: Electric field on biological molecules.
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