Uterine Contractility. Dinaz Lahewala Fall 2011. Outline. Purpose Background Information In-class experiment Questions & Answers. Purpose. Continue discussing properties of Smooth Muscle (esp. of the uterus) Determine the oxytocin dose response in three treatment groups of rats
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Questions & Answers
What are the differences between a human uterus and rat uterus?
-only receptive to sex during "heat“ - estrus-ovulation linked to mating in some species (neuroendocrine reflex results in LH surge)-no sloughing of uterine lining (endometrium)
What role does oxytocin play in:
b) Breast feeding?
Amount of dosage needed in order to produce 50% of the maximum stimulus
In Peripheral Nervous System
In Central Nervous System
Increases heart rate, contracts blood vessels and dilates air passages and participates in the "fight or flight" response of the sympathetic nervous system.
Decreases contractility in uterine smooth muscle
Non selective beta blocker
Competes with adrenergic epinephrine receptors
No significant changes
4) Do oxytocin and acetylcholine exert their effects via different receptors?
5) How does propranolol alter the effects of epinephrine on uterine contractility?
5) Supposed to compete with epinephrine
… We’ll see Pinky. questions…