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Chapters 4 & 5

Chapters 4 & 5. By: Tanisha Bethea. Chapter 4: Mad Sheep. William J. Hadlow commissioned by US to study scrapie http://www.youtube.com/watch?v=S4bhexPs1FA Encouraged to visit kuru exhibit by Bill Jellison. History of Scrapie Studies. Charles Besnoit 1898 McFadyean 1918

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Chapters 4 & 5

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  1. Chapters 4 & 5 By: Tanisha Bethea

  2. Chapter 4: Mad Sheep • William J. Hadlow commissioned by US to study scrapie • http://www.youtube.com/watch?v=S4bhexPs1FA • Encouraged to visit kuru exhibit by Bill Jellison

  3. History of Scrapie Studies • Charles Besnoit 1898 • McFadyean 1918 • Jean Cullie and Paul Louis Chelle

  4. A Vaccine? • Bill Gordon introduces the louping ill vaccine and launches broad scale vaccination • Formaldehyde and alcohol • Kuru is resistant and powerful enough to withstand formaldehyde

  5. Trouble with ARC • Discussion Point: Was the British Government justified in denying Gordon funds? • What impact, if any, do you think this had on the spead of the disease and its research? • Denies Bill Gordon’s request for funds to downplay the economic devastation caused by disease

  6. The U.S. Gets Involved • Were his actions justified? Should his actions have been addressed? • Gordon ignores ARC orders and secures funding from the U.S. • His tests involve goats and sheep

  7. Mad Cow in the U.S. • 1947 Michigan has nations first case of Mad Cow • Move to ban British importations

  8. Chapter 5: Breakthrough • Was this the right move the USDA made? • http://www.youtube.com/watch?v=eloDKqZ4TA4 • Hadlow -> The Lancet -> Gajduskek • Meanwhile USDA has two officials on a national tour killing sheep?

  9. Experiment in Patuxent • Clarence Joe Gibbs is commissioned to lead research deep within a wildlife research facility • Several animals tested with illegally obtained strains of the disease

  10. Dr. Robert C. Reisenger • Is sent to inspect the site at the Patuxent and immediately recognizes that this research is so substandard it should be stopped immediately

  11. Effects of the Patuxent Plant • Inadequate Containment • Crowded shared lab • Soil tainted? • Yes, there was success in the Chimpanzees, however at what costs?

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