Presented by: Nina Chagnon, Date: Jan 17th, 2007

1. Presented by: Nina Chagnon, Date: Jan 17th, 2007 MaRS Discovery District Overview

2. MaRS Discovery District • Why does MaRS exist? • What is MaRS - and what does MaRS do? • What makes MaRS unique? • What lessons have we learned?

3. An Age of Intense Global Competition For resources, capital and talent And Ontario faces significant challenges: • Ontario is an economic powerhouse, but its economy is largely driven by resource and manufacturing industries. • Ontario faces an historic opportunity to profit from its discovery and innovation. • The issue is not a failure to invest in Ontario’s research agenda; instead, relative to other jurisdictions, we are not as successful at capitalizing on this investment in research through effective commercialization. • Ontario has what it takes to compete on the global stage - world class diversified science, skilled human capital, global reach.

4. The global landscape is crowded Ontario faces intense competition KENDALLSQUARE

5. “In a world of global competition, sources of competitive advantage are becoming increasingly localized … true competitive advantage is found within our communities." Michael Porter So how is Ontario going to compete? By embracing a single, fundamental irony:

6. The Origins of MaRS Concerned that Canada was losing ground, a group of 12 visionaries founded MaRS in 2000 to focus the efforts of our research and business leaders on the global innovation challenge. Milestones • Prime pieces of land purchased in downtown Toronto • Early and ongoing support from all levels of government • Significant private sector leadership and financial support • Phase I of the MaRS Centre opened in May 2005 • Phase II is in pre-development; target opening in early 2009 • Full suite of programs and services launched in September 2005

7. What is MaRS? • MaRS connects the communities of science, business and capital to create a more efficient commercialization marketplace. • The MaRS community is built through co-location, catalytic programs and services, and structured networks. • The MaRS community is physically anchored in the MaRS Centre and extends virtually through the MaRS Portal and MaRS Networks. • MaRS is focused on building globally significant companies from Canada’s foundation of science and technology innovation.

8. The MaRS Centre The Physical Platform The MaRS Centre is a convergence facility located in the heart of Toronto’s Discovery District, Canada’s largest research cluster. • Phase I of the MaRS Centre (700K sf, or 77K m2, in 3 buildings) opened in May 2005, and is home to over 60 organizations: leading researchers, technology transfer groups, SMEs, multinationals, service providers, venture capitalists and networking organizations. • Private sector tenants outnumber public sector tenants 3:1. • The MaRS Incubator (35K sf, 3.8K m2) is home to 25 promising emerging life sciences and ICT companies. • The MaRS Collaboration Centre is a conference venue, while the MaRS Venture Group provides hands-on support to companies. • Phase II of the MaRS Centre (~1million sf, 111K m2 ) will be added to Phase I platform to create a global address.

9. Phase I Phase II The MaRS Centre101 College Street, Toronto

10. Intelligent Building Award Global Think Tank Honours MaRS • MaRS was recognized for its ability to leverage emerging IP based technologies to offer a fully connected community for both: • tenants located physically in the building and • a broader stakeholder community connected virtually over broadband networks. • The Intelligent Community Forum (ICF) announced MaRS Centre as the winner of its 2006 Intelligent Building of the Year award. Award acceptedJune 9th, 2006New York City www.intelligentcommunity.org

11. So how is different?

12. 1. MaRS Tenant Mix Covering the Innovation Spectrum Networking and Commercialization Scientific Research & Support BioDiscovery Toronto Industry Capital & Services MERCK Where Patients Come First University of Toronto Asset Management

13. 2. MaRS Discovery District Location Number of Publications by Institution: UofT Ranks 3rd Health Sciences - Number of Publications Indexed by Thomson ISITop 10 Public AAU and G10 Institutions - 2000-2004 Sources: Thomson ISI Canadian University Indicators - Deluxe Edition, 2004 and Thomson ISI U.S. University Indicators - Deluxe Edition, 2004.

14. 2. MaRS Discovery District Location Number of Citations by Institution; UofT Ranks 3rd Health Sciences - Number of Citations Indexed by Thomson ISITop 10 Public AAU and G10 Institutions - 2000-2004 Sources: Thomson ISI Canadian University Indicators - Deluxe Edition, 2004 and Thomson ISI U.S. University Indicators - Deluxe Edition, 2004.

15. 3. MaRS Urban Location Connecting the creative and business assets of the city Gardiner Museum of Ceramic Art Royal Ontario Museum Sunnybrook & Women’s College University of Toronto The MaRS Centre UHN Princess Margaret UHN Toronto General HospitalHospital for Sick children Mount Sinai Toronto Rehabilitation Institute Art Gallery of Ontario Canadian Opera House Major Banks & Investment Firms Discovery District Entertainment District Financial District Creative & Arts District

16. 4. MaRS Strategy Convergence Innovation “The early decades of the 21st Century will be marked by the increased scientific and technological convergence of three fundamental drivers - biotechnology, advanced information technology and nanotechnology [...]. These converging technologies have the promise to achieve tremendous improvements in human capital, innovation, economic performance, and the quality of life“. OECD

17. Science Business Capital 4. MaRS Strategy Convergence Innovation Breakthrough Discoveries Science Talent Economic Results Creativity Creative Communities

18. Science Capital Business BUSINESS SCIENCE CAPITAL 4. MaRS Strategy A New Approach of Commercialization • Results • Slower Process • Increased Risk Old Approach = = Linear • Results • Demand-based, outward-focused innovation • Increased Speed • Improved Scope • Scalability • Multi-dimensional innovation New Approach = = Synergistic

20. Science Business Capital 4. The MaRS Strategy Educational & Networking Events • Convergence Innovation • An annual conference that showcases the invention and creativity of leading thinkers in the convergent worlds of science, technology, business, capital, community and the arts. • Emerging Technologies • Expert perspectives on the latest science and technology research that is of importance to the corporate and investment community. Sessions feature cross-functional presentations by technology and market-experts. • Global Leadership Series • Sessions featuring leaders with demonstrated expertise and success in their field. Topics will be of general interest to a broad audience of business, science and capital participants. • Book Reviews • Author readings and panel reviews of books and journal articles shaping the future of the innovation economy. • Drug Development Discussion Groups • An open forum lead by an industryexpert geared for researchers interested in in drug development • Peer to Peer Series • An intimate forum for entrepreneurs to learn from leaders who have demonstrated success in science and technology. These events also provide an opportunity to network with peers and members of the investment community • Entrepreneurship 101 • Lectures for researchers within the MaRS Discovery District who have no prior business training. This non-credit course program focuses on key elements related to key topics such as: intellectual property, forming a company, investment capital, marketing etc. • Bio-Entrepreneurship • Monthly series designed as follow-on to Entrepreneurship 101, with emphasis the business elements specific to starting up a life sciences company • Best Practices • Workshops on key topics of interest to technology and life sciences entrepreneurs delivered by industry specialists • Creative Communities • Public forums and special events and lectures highlighting the wonders and importance of scientific research and creative energy generated by the arts in our community

21. 4. The MaRS Strategy MaRS Venture Group Mandate Assist start-up teams and growth companies in translating research & innovation into commercial success. Programs & Services • Market Intelligence- Access to leading proprietary research on current markets, investors, and competitive and intellectual property landscapes. • Advisory Services- Delivery of timely strategic and tactical business insights through an in-house team of advisors and network of industry experts. • MaRS Programs- Production of specialized educational programs for researchers, entrepreneurs and investors aimed at encouraging collaboration, skills development and stronger networks. Goals Convert more discoveries into marketplace successes. Strengthen the commercialization skillset in the community as a whole. Accelerate attrition - validate commercial viability sooner. Amplify economic outcomes of high potential technologies.

22. 4. The MaRS Strategy Taking Science out; bringing the Arts in

23. 5. MaRS Networks Strong Regional Partnerships Province of Ontario (Toronto) Edmonton (Ottawa) MaRSLanding(Guelph) BC (Waterloo Region) MaRSLondon(London) Calgary (Hamilton) Saskatchewan Québec Halifax

24. 5. MaRS Networks Helping build international partnerships Global BUSINESS/Global SCIENCE/Global CAPITAL Linking Canada’s Innovation Excellence to International Markets Serving as a Global Address for International Partners ONTARIO CANADA TORONTO

25. MaRS Evolution

26. MaRS Evolution Opportunities and Challenges • People care about this topic • Serendipity is a powerful force • MaRS’ role as a “neutral sandbox” works • The community must own MaRS for it to succeed • Under the right leadership, public/private partnerships can be very effective - and work very quickly • Collaboration is the only way for Canada to achieve critical mass, but true collaboration across expert, cultural and geographic divides is not easy • Commercialization is a global activity – we need to raise awareness of Canada’s assets globally and position our companies for international market success

27. MaRS Venture Group Select Companies ClayTablet Technologies www.clay-tablet.com • Language Translation Workflow Software Diginiche www.octopz.com • Web-Based Collaboration Sofware Skymeter www.appliedlocation.com • Vehicle Location Billing AXS Digital Animation Studio www.axs3d.com • Visulization for Film/TV, Pharma, Biotech, Education, Research Accufusion www.accufusion.com • Digital Laser Parts Manufacturing/Repair Platform