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Multipurpose Prevention Technologies What are they & why do we need them?. [Presenter name, degree, affiliation] [Event title]. [Date]. Multipurpose Prevention Technologies for Reproductive Health. What do women want and need?. Every year. 80 million unintended pregnancies

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multipurpose prevention technologies what are they why do we need them

Multipurpose Prevention TechnologiesWhat are they & why do we need them?

[Presenter name, degree, affiliation]

[Event title]

[Date]

every year
Every year. . .
  • 80 million unintended pregnancies
  • 358,000 women die from pregnancy- related complications
  • 2.5 million people infected with HIV
  • 340 million new gonorrhea, syphilis, trichomonas infections
  • 250,000 deaths from cervical cancer
  • 16 % (15-49) have genital herpes (HSV-2)
products that
products that…

Imagine

  • Prevent pregnancy, HIV/AIDS & STIs at the same time
  • Ensure women’s privacy and safety
  • Are affordable & easily available
  • Are designed by women for their specific needs & preferences
50 years of contraceptive advances
50 years of contraceptive advances

Sheldon Segal

First long term

drug delivery device

Norplant

female controlled mpts
;Female-controlled MPTs

Female Condom

SILCS Diaphragm

Women’s Condom

currently available mpts
Currently available MPTs

Female Condom

Male Condom

emerging mpts
Emerging MPTs

Drug combinations

Multipurpose vaccines

Drug/device combinations

Bacterial therapeutics

Nanoparticals

potential delivery mechanisms for mpts
Potential Delivery Mechanisms for MPTs
  • Devices
    • SILCS Diaphragm
    • Women’s Condom
  • Vaginal Rings
    • Drug release rates differ by ring type
    • Matrix rings vs. Reservoir rings
    • Release rates differ in-vitro from in-vivo
  • Vaginal Tablet
    • Combining different class ART
  • Vaginal Film
    • Nontoxic to cells and flora, fast dissolution
multipurpose vaccines the future
Multipurpose Vaccines: the future
  • Today: Single purpose vaccines (HPV & HBV) are commercially available
  • Next 2 decades: Dual-purpose vaccines that prevent transmission of HSV, HIV, Gonorrhea, Chlamydia, Trichomonas or other STIs
  • Contraceptive vaccines not likely
mpts in the pipeline
MPTs in the Pipeline

Mapping Matrix: www.cami-health.org

cami activities
CAMI Activities
  • MPT Think Tank (May 2011)
  • Target Product Profile working groups (May – Oct 2011)
  • ARHP Conference (September 2011)
  • APHA Conference (October 2011)
  • International MPT Symposium, DC (November 2011)
  • International MPT Symposium, London (January 2012)
  • Microbicides 2012 Conference, Sydney (April 2012)
  • NEXT STEPS
future directions and priorities
Future directions and priorities
  • Support and coordinate novel approaches for multi-disciplinary collaboration
  • Facilitate funding for research & development
  • Expand global and US support
  • Refine priority Product Profiles
  • Assist with clarifying the regulatory pathways
questions
Questions?
  • www.cami-health.org
  • www.arhp.org
  • www.phi.org
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