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Άπνοιες στον Ύπνο και Μεταβολικό Σύνδρομο: Η Αρχή A. Καδίτης PowerPoint PPT Presentation


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Άπνοιες στον Ύπνο και Μεταβολικό Σύνδρομο: Η Αρχή A. Καδίτης. Εργαστήριο Διαταραχών Αναπνοής στον Ύπνο Α ΄ Παιδιατρική Κλινική Πανεπιστημίου Αθηνών Νοσοκομείο Παίδων «Η Αγία Σοφία». Άπνοιες και Μεταβολικό Σύνδρομο. Ορισμός Μεταβολικού Συνδρόμου στα Παιδιά.

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Άπνοιες στον Ύπνο και Μεταβολικό Σύνδρομο: Η Αρχή A. Καδίτης

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(+) 3

  • > 75 -

  • > 95 , ,

  • > 97 mg/dL

  • HDL < 50 mg/dL

  • > 100 mg/dL (> 140 mg/dL)


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Mitchell RB. AT for OSA in Children: Outcome Evaluated by Pre- and Post-Operative Polysomnography. Laryngoscope 2007;117:1844-54

71% of children with postoperative OAHI < 1


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Redline et al risk factors for obstructive sdb in children ajrccm 1999 159 1527 32

Redline et al. Risk Factors for Obstructive SDB in ChildrenAJRCCM 1999; 159:1527-32

  • 399-

  • 2-18

  • AHI 10

    OR 4.59 (1.58-13.33)


Amin et al growth velocity predicts recurrence of sdb 1 year after at ajrccm 2008 177 654 9

Amin et al. Growth Velocity Predicts Recurrence of SDB 1 Year After AT. AJRCCM 2008;177:654-9

70 ( : 10)


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Kaditis et al. Obstructive SDB and Fasting Insulin Levels in non-Obese Children.Pediatr Pulmonol 2005;40:515-23

110 children

2-13 y.o.

  • AHI 5

  • AHI < 5


De la eva r et al metabolic correlates with osa in obese subjects j pediatr 2002 140 654 9

de la Eva R, et al. Metabolic correlates with OSA in Obese Subjects. J Pediatr 2002; 140: 654-9


Li et al ambulatory bp in children with osa a community based study thorax 2009 63 803 9

Li et al. Ambulatory BP in Children with OSA: A Community Based Study. Thorax 2009;63:803-9

306

6-13


A

Redline et al. Association between Metabolic Syndrome and Sleep-Disordered Breathing in Adolescents. AJRCCM 2007;176:401-8

270

13.6 0.7


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Kaditis et al. Urine Levels of Catecholamines in Children with Obstructive Sleep-Disordered Breathing. Pediatr Pulmonol 2009;44:38-45

Norepinephrine (ng/mg of creatinine)

Mild hypoxemia

Moderate hypoxemia

Severe hypoxemia


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Kaditis et al. Effects of AT on R-R interval and BNP Levels in children with OSA. Sleep Med 2011; In press


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;

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Verhulst et al the effect of weight loss on sdb in obese teenagers obesity 2002 17 1178 83

Verhulst et al. The effect of weight loss on SDB in obese teenagers. Obesity 2002;17:1178-83

  • 21 8.714.0

  • z-score 34.8%


Gozal et al metabolic alterations in osa among non obese and obese prepubertal children ajrccm 2008

Gozal et al. Metabolic Alterations in OSA among Non-obese and Obese Prepubertal Children.AJRCCM 2008


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;


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Goodwin et al. Incidence and Remission of SDB and Related Symptoms in 6- to 17-y.o children. J Pediatr 2010;157:57-61


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