11 13 al rahman al quran
This presentation is the property of its rightful owner.
Sponsored Links
1 / 49

11-13 Al Rahman Al Quran PowerPoint PPT Presentation


  • 107 Views
  • Uploaded on
  • Presentation posted in: General

A nd the earth hath He appointed for His creatures. wherein are fruit and sheathed palm trees.husked grain and scented herb. which is it of the favours of your Lord that ye deny?. 11-13 Al Rahman Al Quran. Lipids. D igestion and Absorption. Dietary Lipids.

Download Presentation

11-13 Al Rahman Al Quran

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


11 13 al rahman al quran

And the earth hath He appointed for His creatures. wherein are fruit and sheathed palm trees.husked grain and scented herb. which is it of the favours of your Lord that ye deny?

11-13 Al Rahman Al Quran

Dr Jaria Fatahia


D igestion and absorption

Lipids

Digestion and Absorption

Dr Jaria Fatahia


11 13 al rahman al quran

Dietary Lipids

1.Triglycerides2.Cholesterol3.Cholesterol esters4.Phospholipids

Dr Jaria Fatahia


11 13 al rahman al quran

Digestion of Lipids

  • Enzymes

  • Lipases ( hydrolyze fa from triglycerides)

  • chain lengh

  • pH

  • Emulsification

  • Bile salts

Dr Jaria Fatahia


11 13 al rahman al quran

Differentiate between micelles & chylomicrons

Dr Jaria Fatahia


11 13 al rahman al quran

  • Emulsification of lipids occurs in :

  • Liver

  • Gall bladder

  • Stomach

  • Deudenum

  • Jejunum

Dr Jaria Fatahia


11 13 al rahman al quran

  • Lipases

  • Lingual

  • Gastric

Short and Medium Chain FA

Dr Jaria Fatahia


11 13 al rahman al quran

Pancreatic Enzymes

  • Pancreatic lipase

  • Colipase

  • Cholesterol esterase

  • Phospholipase a2

  • Lysophospholipase

Dr Jaria Fatahia


11 13 al rahman al quran

  • Lipases

  • Colipase

  • (activated by trypsin)

  • Pancreatic lipase

  • FA of all chain lengths

  • Position 1 & 3 of tg

  • Producing free fa & 2 mag

Dr Jaria Fatahia


11 13 al rahman al quran

Control of lipid

digestion

Cholecystokinin

Secretin

Dr Jaria Fatahia


11 13 al rahman al quran

2 MONOACYLGLYCEROL

TRIACYLGLYCEROL

Dr Jaria Fatahia


11 13 al rahman al quran

Cholesterol esterase

(requires bile salts)

Dr Jaria Fatahia


11 13 al rahman al quran

Phospholipase A2

activated by trypsin

Requires bile salts

PHOSPHOLIPID

LYSOPHOSPHOLIPID

Dr Jaria Fatahia


11 13 al rahman al quran

Lysophospholipase

LYSOPHOSPHOLIPID

GLCERYLPHOSPHORYL BASE

Dr Jaria Fatahia


11 13 al rahman al quran

CCK

Pancreatic enzymes

Contraction of gall bladder

Bile Salts

( hydrophobic and hydrophilic)

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


Storing fat

Storing fat

  • TG in blood (CM & VLDL)

  • Insulin activates LPL on vessel wall

  • LPL binds CM or VLDL & extracts TG

  • Breaks down TG into Glcerol & 3 Fas

  • Enter cell

Dr Jaria Fatahia


11 13 al rahman al quran

Dr Jaria Fatahia


11 13 al rahman al quran

______________

C-C C-C C-C

C-C C-C C-C

C-C C-C C-C

C-C C-C C-C

C-C C-C C-C

C-C C-C C-C

C-C C-C C-C

C-C C-C C-C

C-C-C

_____________

_____________

C-C

Krebs

ATP

ETS

Dr Jaria Fatahia


11 13 al rahman al quran

Clinical aspects

lipid digestion

  • Alcohol excess

  • Obstructive jaundice

  • Abetalipoproteinemia

  • Cystic fibrosis

Dr Jaria Fatahia


11 13 al rahman al quran

Alcohol excess

  • Inflammatory process in pancreas

  • Proteinaceous plugs in small pancreatic ducts

  • back pressure injury

  • autodigestion of acini

Dr Jaria Fatahia


11 13 al rahman al quran

Alcohol excess

  • C/F

    • Steatorrhea

  • Treatment

    • Commercial preparation of pancreatic enzymes

    • Avoid alcohol

Dr Jaria Fatahia


11 13 al rahman al quran

Obstructive Jaundice

  • Obstruction of common bile duct

  • Cholestasis

  • Dietary fats not readily emulsified & digested

Dr Jaria Fatahia


11 13 al rahman al quran

Obstructive Jaundice

  • C/F

  • Jaundice

  • Clay colored stool

  • Dark urine

  • Fat soluble vitamin deficiency

Dr Jaria Fatahia


11 13 al rahman al quran

Abetalipoproteinemia

  • Cannot form chylomicrons or VLDL

  • TG accumulate in intestinal & liver cells

  • Blood lipoproteins low

  • Deficiency of fat sol vitamins & essential FA

Dr Jaria Fatahia


11 13 al rahman al quran

In abetalipoproteinemia following is not present in blood?

HDL

Chylomicrons

LDL

Dr Jaria Fatahia


11 13 al rahman al quran

The end

Dr Jaria Fatahia


11 13 al rahman al quran

EXCELLENT!

Dr Jaria Fatahia


11 13 al rahman al quran

TRY AGAIN!

Dr Jaria Fatahia


11 13 al rahman al quran

SORRY!

Dr Jaria Fatahia


Human vs cow s milk

Human vs cow’s milk

Human

  • Long chain polyunsaturated fa

  • Important for brain development

  • Pancreatic lipase & bile salts low in newborn

  • Lingual & gastric lipases

  • Acid stable lipase

Cow’s

  • Short and medium chain FA

  • do not require bile salts

  • Not packaged in chylomicrins

  • enter portal blood rather than lymph

  • Bound to serum albumin

Dr Jaria Fatahia


  • Login