Tuberculosis research funding
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Tuberculosis Research Funding. Erin S. Dante H. Background. One third of the world’s population is infected with TB . - In 2012, nearly 9 million people around the world became sick with TB disease. -There were around 1.3 million TB-related deaths worldwide . Background.

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Tuberculosis Research Funding

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Tuberculosis research funding

Tuberculosis Research Funding

Erin S.

Dante H.


Background

Background

  • One third of the world’s population is infected with TB.

    -In 2012, nearly 9 million people around the world became sick with TB disease.

    -There were around 1.3 million TB-related deaths worldwide.


Background1

Background

  • TB is a leading killer of people who are HIV infected.

  • A total of 9,945 TB cases (a rate of 3.2 cases per 100,000 persons) were reported in the United States in 2012.


Claims

Claims

  • Research and funding are needed in order to find effective ways to implement new tools and approaches in resource-limited environments, this includes clinical and operations research, program and policy design, and monitoring and evaluation.

  • Funding should focus on approaches to screening, diagnosing, case-finding, and curing TB to stop the spread of disease and development of better drugs.


Budget timeline

Budget Timeline


Tuberculosis impact

Tuberculosis Impact

Year 2015

2.5 Billion Dollars:

  • will be used to conduct global research on impact of Tuberculosis

  • Who the disease infects

    • Ages most vulnerable to the disease

    • Men v Women

    • Children vs Elderly

    • Ethnic Groups

    • Countries/Regions


Medication and prevention

Medication and Prevention

Year 2020

2.5 Billion Dollars :

  • will be used on drug developments and vaccines to prevent and cure Tuberculosis.

  • Host Doctoral Scientist and Pharmaceutical Companies to collaborate on drug developments.

  • Focused education in targeted underprivileged areas.


Trials

Trials

Year 2025

2.5 Million Dollars:

  • will be used on Clinical Trials

  • Will include human volunteers

  • About 7,000 participants nation wide

  • Studies will cover a span of 5 years


Distribution

Distribution

Year 2030

2.5 Million Dollars:

  • Dollars will be used on Mass Drug Production and Distribution

  • Shipping

  • Packaging

  • Marketing


Evidence

Evidence

  • The challenge is even greater than it was in the 1940s and 50s when most of the current TB drugs were discovered because

    • the bar for safety is much higher now; and

    • drugs need to be compatible with those used for treating HIV/TB co-infections.


Evidence1

Evidence

  • Finding new drugs for any disease is a long and expensive process.

  • funding for neglected diseases in general and TB drug discovery specifically remains miserably inadequateas compared to research and funding for anti-wrinkle, baldness, and cosmetic surgeries.


Concerns

Concerns

  • Some patients may still have the disease even after clinical trials

  • Budgeting could become inadequate because of economy and inflation progressing over the next 20 years


Resources

Resources

  • http://www.cdc.gov/tb/topic/globaltb/default.htm

  • http://www.stoptb.org/global/research/areas.asp

  • http://www.fda.gov/drugs/developmentapprovalprocess/conductingclinicaltrials/default.htm


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