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Tuberculosis Research Funding. Erin S. Dante H. Background. One third of the world’s population is infected with TB . - In 2012, nearly 9 million people around the world became sick with TB disease. -There were around 1.3 million TB-related deaths worldwide . Background.

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background
Background
  • One third of the world’s population is infected with TB.

-In 2012, nearly 9 million people around the world became sick with TB disease.

-There were around 1.3 million TB-related deaths worldwide.

background1
Background
  • TB is a leading killer of people who are HIV infected.
  • A total of 9,945 TB cases (a rate of 3.2 cases per 100,000 persons) were reported in the United States in 2012.
claims
Claims
  • Research and funding are needed in order to find effective ways to implement new tools and approaches in resource-limited environments, this includes clinical and operations research, program and policy design, and monitoring and evaluation.
  • Funding should focus on approaches to screening, diagnosing, case-finding, and curing TB to stop the spread of disease and development of better drugs.
tuberculosis impact
Tuberculosis Impact

Year 2015

2.5 Billion Dollars:

  • will be used to conduct global research on impact of Tuberculosis
  • Who the disease infects
    • Ages most vulnerable to the disease
    • Men v Women
    • Children vs Elderly
    • Ethnic Groups
    • Countries/Regions
medication and prevention
Medication and Prevention

Year 2020

2.5 Billion Dollars :

  • will be used on drug developments and vaccines to prevent and cure Tuberculosis.
  • Host Doctoral Scientist and Pharmaceutical Companies to collaborate on drug developments.
  • Focused education in targeted underprivileged areas.
trials
Trials

Year 2025

2.5 Million Dollars:

  • will be used on Clinical Trials
  • Will include human volunteers
  • About 7,000 participants nation wide
  • Studies will cover a span of 5 years
distribution
Distribution

Year 2030

2.5 Million Dollars:

  • Dollars will be used on Mass Drug Production and Distribution
  • Shipping
  • Packaging
  • Marketing
evidence
Evidence
  • The challenge is even greater than it was in the 1940s and 50s when most of the current TB drugs were discovered because
    • the bar for safety is much higher now; and
    • drugs need to be compatible with those used for treating HIV/TB co-infections.
evidence1
Evidence
  • Finding new drugs for any disease is a long and expensive process.
  • funding for neglected diseases in general and TB drug discovery specifically remains miserably inadequateas compared to research and funding for anti-wrinkle, baldness, and cosmetic surgeries.
concerns
Concerns
  • Some patients may still have the disease even after clinical trials
  • Budgeting could become inadequate because of economy and inflation progressing over the next 20 years
resources
Resources
  • http://www.cdc.gov/tb/topic/globaltb/default.htm
  • http://www.stoptb.org/global/research/areas.asp
  • http://www.fda.gov/drugs/developmentapprovalprocess/conductingclinicaltrials/default.htm
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