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Nanoparticle Properties. System Properties. Social Properties. Functional Assays. Measurement in prescribed system Quantifies a meaningful process for exposure, hazard or both. Exposure. Hazard. RISK. Data in the CEINT NanoInformatics Knowledge Commons (NIKC). Characterization.
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Nanoparticle Properties System Properties Social Properties Functional Assays • Measurement in prescribed system • Quantifies a meaningful process for exposure, hazard or both Exposure Hazard RISK
Data in the CEINT NanoInformatics Knowledge Commons (NIKC) • Characterization • Meta-Data Bibliometrics Analytical Protocols (e.g. equipment, methods, temporal and spatial data) • Functional Assays • Intermediary, semi-empirical parameters that bridge the gap between nanomaterial properties and potential outcomes • Intrinsic NP • Properties • Surface Affinity • Dissolution Rates • In-vitro Bioassays • Extrinsic NP • Properties • Social& • Engineered • Properties • System • Properties Experimental Protocols (e.g. methods, temporal and spatial data) • Hazard Endpoints • Exposure Endpoints Biomagnification Persistence Bioaccumulation Bioactivity Endpoints Transformations Environmental accumulation Ecological Endpoints e.g. nutrient cycling Mobility
NanoPHEAT • Matrix Release factor: MRF • NICK • Response • q : w.% of NMs in the product • M : mass of product in the system • System: Becker, mesocosm, the house etc • Matrix Release Factor: fraction of NMs in a composite that are released. • Dose