Chemotherapeutic drug administration
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Chemotherapeutic Drug Administration . Prepared By : Miss. Sana’a AL- Sulami Teacher Assistant . Outlines : . Definition of Chemotherapeutic Drug Administration Administration of Chemotherapeutic Agents Dosage of chemotherapeutic administration

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Chemotherapeutic drug administration

Chemotherapeutic Drug Administration

Prepared By :

Miss. Sana’a AL-Sulami

Teacher Assistant

Outlines :

  • Definition of Chemotherapeutic Drug Administration

  • Administration of Chemotherapeutic Agents

  • Dosage of chemotherapeutic administration

  • Equipment of chemotherapeutic drug administration

  • Implementation of administration chemotherapeutic drugs.

Chemotherapeutic drug administration1
Chemotherapeutic Drug Administration :

  • Administration of chemotherapeutic drugs requires skills in additional to those used when giving other drugs .

  • For example some drugs require special equipment or must be given through unusual route.

Chemotherapeutic drug administration2
Chemotherapeutic Drug Administration :

  • Others drugs need protection from the light

  • specially trained nurses and physicians should give chemotherapeutic drugs.

Administration of chemotherapeutic agents
Administration of Chemotherapeutic Agents

  • Chemotherapeutic agents may be administered in the hospital, clinic, or home setting by topical, oral, intravenous, intramuscular, subcutaneous, arterial, intracavitary.

  • The administration route usually depends on the type of agent, the required dose, and the type, location, and extent of tumor being treated.


  • Dosage of antineoplastic agents is based primarily on the

    • patient’s total body surface area

    • previous response to chemotherapy or radiation therapy

    • major organ function.

Complication of chemotherapeutic drugs
Complication of Chemotherapeutic Drugs:

  • Nausea and vomiting

  • Intestinal irritation

  • Stomatitis

  • Hearing loss

  • Anemia

  • Alopecia

Complication of chemotherapeutic drugs1
Complication of Chemotherapeutic Drugs:

  • Diarhea

  • constipation

  • Inflammation, ulceration, necrosis and loss of vein patency.

Equipment :

  • 1-Prescribed drug

  • 2-Gloves

  • 3-Aluminum foil

  • 4-Normal saline solution

  • 5-Syringe and needles

  • 6-Normal pump or controller


  • Assess the patient's physical condition, and review his medical history

  • Make sure you understand what chemotherapeutic agent needs to be given and by what route, and provide the necessary teaching and support to the patient and his family


  • Confirm the patient's identity according to your facility policy

  • Determine the best site to administer the drug, When selecting the site, consider drug compatibilities, frequency of administration


  • Evaluate your patient's condition, the result of

    recent laboratory studies .

  • Determine whether the patient has received

    chemotherapy before ,and note the severity of any adverse effects.

  • Check his drug history for medications that may interfere with chemotherapy. Talk with the physician or pharmacist before you give it.


  • Check the patient's chart for complete

    chemotherapy protocol order, including the

    patient's name and dosage, and route ,rate and frequency of administration

  • Check to see whether the physician has ordered an antiemetic, fluids , a diuretic, or electrolyte supplements to be given before , during , or after chemotherapy administration.


  • Evaluate the patient's and his family's understanding of chemotherapy, and make sure the patient or a responsible family member has signed the consent form.

  • Put on gloves. Keep them on through all stages of handling the drug including preparation, I.V. tubing, and administration.


  • Before administering the drug avoid giving chemotherapeutic drugs through an existing I.V. line.

  • To identify an administration site, examine the patient's veins starting with his hands and proceeding to his forearm.

  • When an appropriate line is in place, infuse 10 to 20 ml of normal saline solution to test vein patency .


  • Never test vein patency with a chemotherapeutic drug. Next, administer the drug as appropriate.

  • Closely monitor the patient for signs of hypersensitivity reaction.

  • After infusion of the medication, infuse 20 ml of normal saline solution. Do this between administrations of different chemotherapeutic drugs and before discontinuing the I.V. line.


  • Dispose of used equipment in properly container.

  • Wash your hands thoroughly with soap and warm water after giving any chemotherapeutic drug


  • Location & description of the I.V site before treatment

  • Record the drug & dosage administration

  • Sequence of drug administration

  • Needle type and the size used

  • Amount & type of flushing solution


  • Document any adverse reaction

  • Patient’s tolerance of treatment.

  • Topics discussed with the patient and his family.