Essential Biochemistry Third Edition Charlotte W. Pratt | Kathleen Cornely. Lecture Notes for Chapter 10 Signaling. KEY CONCEPTS: Section 10-1. Receptor-ligand binding is described in terms of a dissociation constant.
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Charlotte W. Pratt | Kathleen Cornely
Lecture Notes for
Antagonist of Adenosine Receptor – Caffeine binds but does NOT elicit a response
Natural agonist for Adenosine Receptor
Physiological ligands for the β-adrenergic receptor
G Protein with GDP (orange) bound
Signaling is limited by the GTPase activity of the α subunit
R = Regulatory subunit
C = Catalytic subunit
Zoomed in view of active site
Calmodulin has an extended shape.
Calmodulin wraps around
its protein target!
Light blue = inactive receptor
Dark blue = activation loop
Light green = active receptor
Dark green = activation loop
The Glucocorticoid Receptor-DNA Complex