Predicting the Chronic Effects of PAHs using the Target Lipid Model of Narcotic Toxicity
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Predicting the Chronic Effects of PAHs using the Target Lipid Model of Narcotic Toxicity. Joy McGrath Dominic Di Toro HydroQual, Inc. SETAC North America 27 th Annual Meeting Montreal, Canada November 5-9, 2006. Acknowledgement. Funding for this project was provided by

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Predicting the Chronic Effects of PAHs using the Target Lipid Model of Narcotic Toxicity

Joy McGrath

Dominic Di Toro

HydroQual, Inc.

SETAC North America 27th Annual Meeting

Montreal, Canada

November 5-9, 2006


Acknowledgement

Acknowledgement Lipid Model of Narcotic Toxicity

Funding for this project was provided by

the Coastal Response Research Center

www.crrc.unh.edu


Acute toxicity qsars for narcotics
Acute Toxicity QSARs for Narcotics Lipid Model of Narcotic Toxicity


Computation of effect concentrations
Computation of Effect Concentrations Lipid Model of Narcotic Toxicity


Acute effects lethality single exposures
Acute Effects (lethality) – Single Exposures Lipid Model of Narcotic Toxicity

Water Column

Sediment







Comparison of hc5s and noecs for pahs
Comparison of HC5s and NOECs for PAHs Mixtures

WATER

SEDIMENT


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