1 / 18

Redesigning Carotid Angioplasty Protection Device Filters through In Vitro Experiments

This project aims to perform flow motion analysis on various stroke reduction filters used in carotid angioplasty procedures. By redesigning these filters based on the analysis, the goal is to create more effective and efficient protection devices to reduce the risk of thromboembolism.

dwayneford
Download Presentation

Redesigning Carotid Angioplasty Protection Device Filters through In Vitro Experiments

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. In Vitro Experiments and Redesign of Protection Device Filters Used in Carotid AngioplastyErdrin AzemiHeather GrayEmily MinerAGM Inc. Project Advisor: Ender A. Finol, Ph.D.Project Director: Mark H. Wholey, M.D.Senior DesignBioE1160

  2. Overview • Objective: • To perform flow motion analysis on several Stroke Reduction Filters currently available in the market • Protection device filters are used during angioplasty procedures to reduce the risk of thromboembolism • Redesign the components of these filters, as we see necessary, following flow motion analysis

  3. Atherosclerotic Plaque • Stroke is the 3rd • leading cause of • death in the U.S. • Atherosclerotic • plaque can cause • stroke Schematic of Plaque in the Carotid Artery2

  4. 3 2 1 Angioplasty Procedure

  5. Project Goals • To test four current endovascular filters on the market: (Angioguard TM, Acunet TM, EPI Filter WireTM, and Neuroshield TM) • To redesign a more effective and efficient endovascular filter protection device • To accomplish all the testing experiments by the end of January

  6. Current Filters EPI Filter Wire TM Neuroshield TM Angioguard TM

  7. Features & Benefits of the Filter Features • Efficiently catches clots • Provide more reinforcements around Nitinol ring • Better labeling of delivery and retrieval sheaths Benefits • Lowers the risk of thromboembolism • Easier to guide through different size arteries and lasts duration of surgery • Reduces user confusion

  8. Description Guide Wires AGMshield EPI Filter Wire TM Angioguard TM

  9. Design Alternatives • We are currently addressing problems with the size and stability of the NitinolTM ring, clot catching efficiency, and the labeling of the delivery and retrieval sheaths • After the appropriate testing, we plan to redesign the above components, hopefully maximizing efficiency and reaching our goals

  10. Competitive Analysis Competitors • There are several protection device filters on the market. In our study, we will be dealing with the 4 that we have previously mentioned. We will consider these to be our direct competitors Strengths • Relative to other competitors, our design approach will piece together all of the most effective parts of each filter tested Weaknesses • Because of our limited resources, there are surely several problems that we will be unable to address at this moment

  11. Technology Experimentation • We will be using a in-vitro flow loop provided by Carnegie Mellon University • Existing filters Engineering Modeling • SolidWorksTM Modeling will be used to develop our design

  12. Team/Resources Advisors • Dr. Endor Finol • Dr. Mark Wholey Equipment/Support • Flow pump and lab provided by CMU • Filters provided to Dr. Wholey by various suppliers: AngioguardTM, AcunetTM, EPI Filter WireTM, and NeuroshieldTM Location • Carnegie Mellon University Laboratory Manufacturing • Will be limited by funds and advisor needs

  13. Schedule Fall 2003 • Design History File • Meeting with advisors • Literature Research • Prepare for Presentation • Flow Loop Set Up • Perform Preliminary Tests

  14. Schedule Spring 2004 • Perform experiments and achieve data • Meet with advisors • Filter Redesign • Design Implementation • Final Paper and Presentation

  15. Team Chores

  16. Current Status We have completed the following tasks: • Meeting with advisors • Completed an initial design history file • Prepare for Presentation • Flow Loop Set Up (to be completed 12/5-pm)

  17. Acknowledgements Thank You: • Mark Wholey, MD • Ender Finol, PhD • Mark Gartner • Bioengineering Department, University of Pittsburgh • Elena DiMartino • Carnegie Mellon University

  18. THANK YOU! ?

More Related