Background for LVAD papers. Topics. Heart anatomy and function (Ashley) Heart failure (Kelsey) Ventricular assist devices (Julianne) NY Heart Association Functional Class (Philicia) MN Living with HF Questionnaire (Suzy). Heart anatomy and function. 1. 7. 6. 12. 9. 8. 2. 5. 11. 10.
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Fig 1: Diagram of ThoratecHeartMate II in relation to heart
How did we get here?
1 million hospital discharges
Scarcity of organ donors
2200 transplants/ year
Bridge to Transplant or Destination Therapy
Benefits of Destination Therapy:
Survival benefit in end stage heart failure
2 year survival – 77% vs. 8-10% with medications
Gastro-intestinal bleeding (22%)
Major/ Sepsis (17%)
Fig 2: Jarvik 7: Heart
Fig 3: Thoratec
Badiwala, M.V.; Rao, V. “Left ventricular device as destination therapy: are we there yet?” Current Opinion in Cardiology 2009; 24(2): 184–189.
Rose, E. A.; Gelijns, A.C.; Moskowitz, A.J, et. al. “Long-Term Use of a Left Ventricular Assist Device for End-Stage Heart Failure” N Engl J Med 2001; 345:1435-1443
NY Heart Association Functional Class
MN Living with HF Questionnaire