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BUSINESS OPPORTUNITIES IN BIOTECHNOLOGY IN INDIA. P. K. Ghosh, Ph D Managing Director KEE GAD Biogen Pvt. Ltd., New Delhi (Former Adviser DBT, GOI) [email protected] March 06, 2009. INDIAN EFFORTS TO SUSTAIN EMINENCE IN BIOTECHNOLOGY: MOSTLY A GOVERNMENT EFFORT.

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business opportunities in biotechnology in india

BUSINESS OPPORTUNITIES IN BIOTECHNOLOGY IN INDIA

P. K. Ghosh, Ph D

Managing Director

KEE GAD Biogen Pvt. Ltd., New Delhi

(Former Adviser DBT, GOI)

[email protected]

March 06, 2009

indian efforts to sustain eminence in biotechnology mostly a government effort
INDIAN EFFORTS TO SUSTAIN EMINENCE IN BIOTECHNOLOGY: MOSTLY A GOVERNMENT EFFORT
  • Government Departments
    • DBT
    • DST
    • DSIR
    • DRDO
    • DOE & Others
  • Autonomous Institutions
    • CSIR
    • ICAR
    • ICMR
    • UGC/AICTE Institutions
    • Other Institutions

P. K. Ghosh

indian biotech in global context
INDIAN BIOTECH IN GLOBAL CONTEXT
  • Publications and Patents filings on the rise
  • Leadership in innovation is yet narrow
  • R&D Institutes & Universities low in Global ranking
  • Research in Industry not significant yet
  • Innovation and Application not strongly linked
  • Academia not ready to take risk for a venture

P. K. Ghosh

health wealth index for development
HEALTH & WEALTH: INDEX FOR DEVELOPMENT

A Country is highly developed if it has……

  • Break through remedies for major diseases like:
    • Cardiovascular diseases
    • Cancer
    • Viral Diseases
    • Killer Bacterial Diseases
  • Abundant availability of Clothing, Food & Drinking water
  • Sound Knowledge and Practice of good Hygiene
  • High Quality Jobs
  • Technologically Advanced Industries

In all the above areas Biotech can make a contribution….

P. K. Ghosh

skills that revolutionized biotechnology
SKILLS THAT REVOLUTIONIZED BIOTECHNOLOGY

rDNAs & MAbs

Protein & DNA Chips

& Microarrays

PCR Technology

Bio-Informatics

Microscopy and Imaging

LC-MS &

MALDI-TOP

Chromatography &

Electrophoresis

Flow-cytometry &

Cell Sorting Techniques

P. K. Ghosh

Proteins & Nucleotide

sequencing

top concerns of indian biotech industry
TOP CONCERNS OF INDIAN BIOTECH INDUSTRY
  • Scarce availability of leaders for company specific needs
  • Inadequate availability of skilled work force
  • Limited resources for research- Internal & External
  • Maintenance of Confidentiality
  • Issues of Intellectual Property
  • Bridging issues between R&D Institutions & Industry
  • Demanding statutory requirements
  • Biased concerns about products by opinion makers
  • Limited linkage between Industry need & Public research

P. K. Ghosh

benefits of technology transfer by r d institutes
BENEFITS OF TECHNOLOGY TRANSFER BY R&D INSTITUTES
  • To push discovery into the market
  • To attract Funding & Industrial Partnership
  • Budding skills can be placed into rewarding projects
  • To earn rewards through income & fame
  • Obliged to be transparent by disclosers – Projects, Employees, Sponsors etc.
  • Economic development and Societal uplift

P. K. Ghosh

slide8

GM- Planting Mats. & Hybrids

Micro-propagation

Bio-fertilizers & Bio-pesticides

Animal Improvement

r-DNA Products, Vaccines & Diagnostics

Monoclonal Antibodies

Stem Cells

Tissue Specific delivery methods

Agriculture

Health Care

BIOTECH APPLICATIONS

Environment

Industry

Enzymes

Fermentation based Products & Food

Biotech Instruments & Equipment

Bio-energy & Bio-fuel

Bioinformatics

Bio-mining

Soil & Water remediation

Bio-safety & GMOs

P. K. Ghosh

business opportunities health care
BUSINESS OPPORTUNITIES: HEALTH CARE
  • rDNA Products & MAbs
    • Cloning, Cell multiplication, Product separation & Formulations
    • Choice of technologies
  • Stem Cell Manipulation
    • Isolation, purification & multiplication of tissue specific stem cells
    • Expertise in Cell re-programming to pluripotency
    • Over expression of certain Genes for Cell re-programming
    • Retro & Non-retroviral means of over expression of target genes
  • Tissue Specific Delivery Technologies
    • Choice of Bio-degradable polymers & modification methods
    • Choice of technologies for production of precise Nano-particles

P. K. Ghosh

business opportunities agriculture
BUSINESS OPPORTUNITIES: AGRICULTURE
  • GM- Seeds: Varieties & Hybrids
    • Choice of right materials
    • Cloning, Micro-propagation & Field Testing
    • Generation of Food & Environmental Safety Information
    • Extensive Public-Private Collaboration involving Opining Makers
  • Animal Improvement
    • Land & Aquatic Animals Identification for Multiplication
    • Choice of Exotic Animal germplasm & Multiplication methods
    • Feed & Fodder Production technologies

P. K. Ghosh

business opportunities industry environment
BUSINESS OPPORTUNITIES: INDUSTRY & ENVIRONMENT
  • Industry
    • r-DNA methods of producing Enzymes
    • Fermented Food & Beverages
    • Software Development for use in Biotech operations
    • Biotech Instruments through Electronics, Software & New Materials
    • Biomass Multiplication & Bio-fuel
  • Environment
    • Biosafety Information generation for commercial use of GMOs
    • Degraded/ Polluted Soil & Water Remediation methods

P. K. Ghosh

biotech product development trend
BIOTECH PRODUCT DEVELOPMENT TREND
  • Drugs & Pharmaceuticals for Human
  • Isolating/Developing & Multiplying Totipotent Stem Cells
  • Genetically Modified Seeds for Agriculture
  • Instruments for Biotechnology
  • Bioinformatics

P. K. Ghosh

biotech drugs innovation process
Biotech drugs innovation process

Marketing feedback analysis

Strong Industry Motivation for Success

Production Unit setting up & implementation into valuable form

Phase I, II, III Studies

Marketing Strategy

Animal Studies

Actors

Money Spent

Pilot Development

Technology Development & Transfer

Regulatory Approval

Proof of Concept

R&D Institutes

New Idea/ Research

0

5

10

15

Time (Years)

what are the survival lanes
WHAT ARE THE SURVIVAL LANES?
  • To Intensify Basic Research
  • To Develop Novel Methods for Bio-generics
  • Mass Production of Multivalent Vaccines
  • Mass Production of Cheap Diagnostics
  • Novel Drug Delivery & Nanotechnology
  • GM Varieties from Public Institutions
  • Micro-propagation of elites
  • Industrial Enzymes by r-DNA technology
  • Mass Composting of wastes
  • Enzyme Enriched Food & Neutraceuticals
  • Bio-energy & Bio-fuels

P. K. Ghosh

thank you
THANK YOU

Turbulence ahead…

P. K. Ghosh

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