Lecture 10 second messengers iv niric oxide cgmp and ros signalling
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Lecture 10 – Second Messengers IV – Niric Oxide, cGMP , and ROS Signalling PowerPoint PPT Presentation


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Lecture 10 – Second Messengers IV – Niric Oxide, cGMP , and ROS Signalling. BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F. CSB Fig 02:01 Cell signalling pathways .

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Lecture 10 – Second Messengers IV – Niric Oxide, cGMP , and ROS Signalling

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Lecture 10 second messengers iv niric oxide cgmp and ros signalling

Lecture 10 – Second Messengers IV –Niric Oxide, cGMP, and ROS Signalling

BIOL 5190/6190 Cellular & Molecular Singal Transduction

Prepared by Bob Locy

Last modified -13F


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 02:01 Cell signalling pathways

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Transducers second messengers ii

Transducers Second Messengers II

  • Nitric Oxide

    • cyclic GMP Signaling

  • Redox signaling

  • ROS signaling


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:45 NO and cyclic GMP signalling

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:46 NO synthase mechanism

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:47 eNOS activation

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:48 Summary of redox signalling

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:49 Reactive oxygen species (ROS)

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:50 Sites of ROS formation

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:51 Plasma membrane ROS formation

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:52 GSH/GSSG couple

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:53 H2O2 metabolism

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:54 Peroxiredoxin catalytic cycles

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:55 Reversible & irreversible ROS oxidations

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:56 ROS formation and action

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:57 Recovery of protein oxidation

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:58 Thimerosal-induced Ca2+ signalling

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

Module 2:59 Figure ROS effects on Ca2+ signalling

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:60 ROS microdomains

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


Lecture 10 second messengers iv niric oxide cgmp and ros signalling

CSB Fig 2:61 ROS microdomains

Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012


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