Porcine rhabdomyosarcoma
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Porcine Rhabdomyosarcoma. Valerie Cummings, DVM Anatomic Pathology Intern Tuskegee University College of Veterinary Medicine. Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only. Case Presentation.

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Porcine rhabdomyosarcoma

Porcine Rhabdomyosarcoma

Valerie Cummings, DVM

Anatomic Pathology Intern

Tuskegee University

College of Veterinary Medicine

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Case presentation
Case Presentation

  • A four week old, Landrace/Yorkshire, male porcine presented for necropsy in February 2006 (n = 120)

  • Clinical presenting complaint – severe respiratory distress

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Gross findings
Gross Findings

  • Large mass involving the anterior cervical region

  • Transverse sectioning  ~ 4 cm x 4 cm x 4 cm, firm, multinodular grayish-white mass attached to C1 and C2

  • Infiltration of mass into adjacent skeletal muscle

  • Lungs – Mild interlobular edema

    Liver – Focal, 1 mm x 1 mm, grayish white areas (capsular

    and parenchymal in origin)

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Gross findings1
Gross Findings

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Histologic findings
Histologic Findings

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Histologic findings1
Histologic Findings

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Histologic findings2
Histologic Findings

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Histologic findings3
Histologic Findings

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Special stain mallory s phosphotungstic acid hematoxylin ptah
Special stain – Mallory’s Phosphotungstic acid hematoxylin (PTAH)

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Immunohistochemistry vimentin
Immunohistochemistry - Vimentin hematoxylin (PTAH)

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Immunohistochemistry alpha sarcomeric actin
Immunohistochemistry - Alpha sarcomeric actin hematoxylin (PTAH)

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Immunohistochemistry myogenin
Immunohistochemistry - Myogenin hematoxylin (PTAH)

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


Diagnosis
Diagnosis hematoxylin (PTAH)

  • Embryonal Rhabdomyosarcoma, invasive, porcine

Presented at SEVPAC 2007 – Permission granted for use on SEVPAC website only


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