Chronic myeloproliferative disease. CML: chronic myeloid leukemia CNL: chronic neutrophilic leukemia PV: Polycythemia vera PMF: primary myelofibrosis ET: Essential Thromboctthemia CEL- NOS:chronic eosinophilic leukemia, not otherwise spesified Mastocytosis
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PV, proliferative phase. The bone marrow biopsy is hypercellular withtrilineagehematopoiesis and loose clusters of pleomorphicmegakaryocytes. Such atypicalmegakaryocytic hyperplasia of PV is not present in secondary polycythemias, and marrowfibrosis is typically minimal in this stage of the disease.
سه ویژگی مهم:
thrombocytosis with large and giant platelets and normal erythrocytes (as shown here). A mildleukocytosis, usually less than 30,000/μL, also may be present, as can circulatingmegakaryocyte nuclear fragments or even micromegakaryocytes.
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درجه های والا وآسایش همیشگی می رسد.
امام علی (ع)