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HTLV-4(ORFIV) ---------------------------------------------

Active region. HTLV-4(ORFIV) --------------------------------------------- HTLV-1(p13 II ) MLIISPLPRVWTESSFRIPSLRVWRLCTRRLVPHLWGTMFGPPTS 45 STLV-2(ORFII) MPFFSPLSRFRTEPPLWIPSLRVWRLCSSRLVSRFRWALFHPPAP 45

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HTLV-4(ORFIV) ---------------------------------------------

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  1. Active region HTLV-4(ORFIV)--------------------------------------------- HTLV-1(p13II) MLIISPLPRVWTESSFRIPSLRVWRLCTRRLVPHLWGTMFGPPTS 45 STLV-2(ORFII) MPFFSPLSRFRTEPPLWIPSLRVWRLCSSRLVSRFRWALFHPPAP 45 HTLV-3(ORFIV) SNLQKFYSLVSPFPRFRTEPSLRVPCLRFRRLCTGRLVPHFWGALFRSATP 51 HTLV-2(p28XII) MFHPPTS 7 HTLV-4(ORFV) HTLV-4(ORFIV) ----------MDHLGPHRWTSCRLASPIPYPSPPLLPHPTNLQDPQSPYPTNHSCHPQGSTLLLSVRAEA 60 HTLV-1(p13II) SRPTGHLSRAS.........RY..S.TV....T......EM.---------------------------- 87 STLV-2(ORFII) ACPSRHLPGAPA........R...S.......A......E......G.HSPY...L..D..R.FPIH.-- 113 HTLV-3(ORFIV)PCPTGHVPRTS.Y.......R.Q.S.T.....T......E.YPH..GSH.P..C.D..D.SI..PR.--- 118 HTLV-2(p28XII)TCPPGHLSRAPT........R.Q.S..............E..K...G...SH...L.....C...IN.K. 77 HTLV-4(ORFV) ---------------------------------------------------------------------- 1 HTLV-4(ORFIV)QPLPQRMS 68 HTLV-1(p13II) -------- 87 STLV-2(ORFII)-------- 113 HTLV-3(ORFIV)-------- 118 HTLV-2(p28XII)H...KW.PGTNPRGSAPLPRLPRTWPPSPKHLHHLGKNRSMPIPIPAFPTHDMATYTPCHILPPQTIRSL 147 HTLV-4(ORFV)---------------------------------------------M.V.S..L.PHS.....Q..AAWRF 25 HTLV-4(ORFIV)--------------------------------------------------------------------- 68 HTLV-1(p13II) STLV-2(ORFII) HTLV-3(ORFIV) HTLV-2(p28XII) PHQGASKTIRRTSIQNVPTHRDSHSPPGGRPTHHNVPTREGSLYPDCLVYRTSPLSLHLNNPRSNMDLQ 216 HTLV-4(ORFV) SK.C.PQA....PL.TLS...RHNH.A.R..AY.PISACSSTLC.NYLEH....IPAKPDY.WPD...- 93 75% 72% 67% 75% Mitochondrial Targeting Sequence Highly Conserved Region 48% % sim

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