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Cot1- DNA dependent Dyn.Std.Ref.Int. variations

Cot1- DNA dependent Dyn.Std.Ref.Int. variations. Shown Dynamic Stdandard Reference Interval Sets: 1) Cases having better Cot1-DNA suppression of test-DNA than of reference-DNA give: Low ratios for 11q13, 16p, 17, 19, 22 and peri-centromeric regions of 1q, 2p, 7, 9, 10p, 13q, 14q, 15q & 18p

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Cot1- DNA dependent Dyn.Std.Ref.Int. variations

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  1. Cot1- DNA dependent Dyn.Std.Ref.Int. variations Shown Dynamic Stdandard Reference Interval Sets: 1) Cases having better Cot1-DNA suppression of test-DNA than of reference-DNA give:Low ratios for 11q13, 16p, 17, 19, 22 and peri-centromeric regions of 1q, 2p, 7, 9, 10p, 13q, 14q, 15q & 18p Worst are 19, 17 and 16p 2) Our current routine set of Dynamic Standard Reference Intervals: I.e. cases having too bad Cot1-DNA suppression or showing clear imbalance of these do not contribute. 3) Cases having worse Cot1-DNA suppression of test-DNA than of refeference-DNA give: High ratios for 11q13, 16p, 17, 19, 22 and peri-centromeric regions of 1q, 2p, 7, 9, 10p, 13q, 14q, 15q & 18p Worst are 19, 17 and 16p Note 1: The automatic Cot1-DNA correction cannot correct for the above special low or high ratios. Note 2: All sets are scaled automatically to fit a random case that looks like the routine set of Std.Ref.Int. Use arrow right to see next slide or arrow left to see the previous.

  2. 1) Notice the low ratios of 19, 17 and 16p

  3. 2) Our current routine set

  4. 3) Notice the high ratios of 19, 17 and 16p

  5. End

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